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Chronic Fatigue Syndrome (CFS): a novel disorder with cutaneous manifestations

  [ 28 votes ]   [ Discuss This Article ]
www.ProHealth.com • February 3, 1994


Persistent and disabling fatigue associated with low-grade fever and
other constitutional symptoms, without any known disorder that
accounts for it, is recognized as chronic fatigue syndrome
(CFS). Skin lesions occur in 10-35% of patients, but their
description is inaccurate. Recurrent aphthous stomatitis or
persistent Epstein-Barr virus (EBV)-related erythema
multiforme have also been reported. Patients may be diagnosed
as having CFS only when they fulfill at least 2 major and 8
minor criteria. Major criteria are the presence of
debilitating fatigue persisting or recurring for at least 6
months and the absence of any other medical disorder that may
explain it. Although different viral or nonviral etiologies
have been documented, evidence implicating EBV is gaining
support.

Rebora A, Drago F




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