ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Is a Good Night's Sleep at the Top of Your Wishlist?

Ashwagandha Helps Hormones - Aids Arthritis

Why You Should Be Eating More Porcini Mushrooms

A Breathalyzer for Disease?

How Bacopa Can Help Improve Your Cognitive Function

Magnesium Reduces Diabetes and Helps Keep You Young

Lavender Aromatherapy Can Ease Pre-Op Anxiety

Give Your Health a Much-Needed Boost With Geranium

The Role of Resveratrol in Achieving Optimal Health

Could Coconut Oil Help Reduce Antibiotics?

 
Print Page
Email Article

How Effective are Opioids in Chronic Pain Relief?

  [ 36 votes ]   [ 1 Comment ]
www.ProHealth.com • May 30, 2001



Fentanyl skin patches achieve better pain relief and an enhanced quality of life than sustained release oral morphine, say patients with chronic non-cancer pain in a study in the British Medical Journal.

Patients with chronic non-cancer pain, requiring continuous treatment with potent opioids, were randomly assigned to two groups to assess their treatment preference, pain control, and quality of life. One group received four weeks of treatment with sustained release oral morphine followed by fentanyl patches for four weeks. The second group received the same treatments but in reverse order.

Of 212 patients, 138 (65%) preferred fentanyl patches, whereas 59 (28%) preferred sustained release oral morphine and 15 (7%) expressed no preference. The main reason given for preferring fentanyl was better pain relief, followed by greater convenience and fewer adverse events.

Patients receiving fentanyl also had higher overall quality of life scores than patients receiving morphine. Although the level of adverse events was similar in both treatment groups, more patients experienced constipation with morphine than with fentanyl. These findings confirm that potent opioids can provide satisfactory pain relief for the difficult clinical problem of chronic non-cancer pain, conclude the authors.

In an accompanying editorial, pain specialist Henry McQuay acknowledges that this is a welcome trial in a difficult area, but writes: "Unfortunately the design of the trial means that we have to question the results. Rule one of drug trials that compare different formulations and use subjective outcomes such as patient preference is that the comparison should be done double blind."

However, the authors argue for simple clinical trials based in clinical practice, using outcomes of greater relevance to patients. The ethics of perfect design with placebos and blinding is questionable, especially when such complex trials fail to recruit patients or yield useful results. Treatment options for these patients are limited. As such, this comparative trial may herald a new approach for their care and in ethical clinical trial design.



Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Vitamin D3 Extreme™ Mitochondria Ignite™ with NT Factor®


Article Comments Post a Comment

patch or slow release opioides
Posted by: Bob-Learner
Apr 9, 2009
I am suffering from chronique pain for 14 years and I have tried the patches for a short time and found them effective and to have a little less side effects. My skin reacted to the patch so I would move the place where the patch would go. Workers compensation choose for me the slow realease opioids because they cost less. However I must add that slow release opîoid I use is a lot better than some other similar products I tried but both superior to regular opioid that go my mood to go up and down every 4 hours or less.
Reply Reply
 
Optimized Curcumin Longvida with Omega-3

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength

Natural Remedies

Quercetin: Natural Support for Allergy & Inflammation Relief and More Quercetin: Natural Support for Allergy & Inflammation Relief and More
Top 3 Nutrients to Detox the Liver and Soothe Digestion Top 3 Nutrients to Detox the Liver and Soothe Digestion
How I Found My Long-Lost Energy How I Found My Long-Lost Energy
Physically and Mentally Exhausted? How to Restore Energy at Its Source Physically and Mentally Exhausted? How to Restore Energy at Its Source
Improve Cardiovascular and Metabolic Health with Omega-7 Improve Cardiovascular and Metabolic Health with Omega-7

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map