ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Vitamin D supplements, sleep could help manage pain

Bacopa: The Herb That May Increase Your Brain Power

Lilac Oil: More Than Just for Fragrance

Eat More Yogurt and Avoid Osteoporosis

Safflower: An Economically Important Herb That Can Benefit Humans and Animals Alike

What Is Bilberry Good For?

Coffee, herbal tea may help prevent liver fibrosis

Crafty Uses for Carrot Seed Oil

Resveratrol Improves Arteries

Higher omega 3 levels linked to improved brain blood flow

 
Print Page
Email Article

Ask The Expert: Role of Mycophenolate Mofetil in Lupus Nephritis?

  [ 33 votes ]   [ Discuss This Article ]
www.ProHealth.com • October 9, 2002


Lupus, Sjögren's Syndrome, Scleroderma, and Related Conditions

Ask The Expert: Role of Mycophenolate Mofetil in Lupus Nephritis?

Posted 09/30/2002  from Medscape Rheumatology

Question: What is the role of mycophenolate mofetil in lupus nephritis? Is it superior or equal in effectiveness to cyclophosphamide?

Response  from Arthur Kavanaugh, MD, 09/30/2002

There are several difficulties affecting the ability to assess therapies in a disease such as lupus nephritis. Because of the substantial heterogeneity of the disease process, it is often hard to compare populations treated in one study with those treated in other studies. Also, as medical treatment has evolved over time, there are other factors that affect patient survival and renal and other outcomes. For lupus nephritis, progress in the development of antihypertensive agents and intensive-care unit management probably has had a beneficial role in patient outcome. Thus, it is hard to compare the results observed in a contemporary study with those observed in a study from a decade or 2 in the past.

With these caveats, there have been several studies that have suggested that mycophenolate mofetil may be a useful treatment for lupus nephritis. In a study[1,2] of 42 patients from Hong Kong with World Health Organization type 4 lupus nephritis, the extent of complete remission with mycophenolate was comparable to that achieved with cyclophosphamide (oral, beginning at 2.5 mg/kg/day for 6 months, followed by azathioprine). Tolerability favored mycophenolate. Overall, the data suggest that this may be a viable treatment option for lupus nephritis. However, another consideration that may affect the use of this agent is its relatively high cost.

References

Dooley MA, Cosio F, Nachman P, et al. Mycophenolate mofetil therapy in lupus nephritis: clinical observations. J Am Soc Nephrol. 1999;10:833-839.
Chan TM, Li FK, Tang CSO, et al. Efficacy of mycophenolate mofetil in patients with diffuse proliferative lupus nephritis. N Engl J Med. 2000;343:1156-1162.

About the Panel Members

Arthur Kavanaugh, MD, Director, Center for Innovative Therapy, Division of Rheumatology, Allergy, and Immunology, University of California at San Diego.



Post a Comment

Featured Products From the ProHealth Store
Mitochondria Ignite™ with NT Factor® Vitamin D3 Extreme™ Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%

Natural Remedies

Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed Fight Inflammation and Promote Cognitive Health with High-OPC Grape Seed
Prepare Yourself for Cold & Flu Season Prepare Yourself for Cold & Flu Season
Carry a Massage Therapist in Your Pocket Carry a Massage Therapist in Your Pocket
Block Acid Reflux to Prevent Esophageal Problems! Block Acid Reflux to Prevent Esophageal Problems!
How I Found My Long-Lost Energy How I Found My Long-Lost Energy

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map