ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

Fight Back! Win the War Being Waged Against Your Immune System

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Pumpkin Pie Turmeric Breakfast Smoothie - Vegan + Gluten-Free

Vitamin D supplementation extends life in mouse model of Huntington's disease

Omega-3 fatty acid stops known trigger of lupus

Conquer Your Email Inbox, Increase Productivity and Reduce Stress

Print Page
Email Article

New Treatment Improves Symptoms of Parkinson's Disease

  [ 61 votes ]   [ Discuss This Article ] • April 29, 2002

Susan Mayor, London

Source: (British Medical Journal online)

Patients with advanced Parkinson's disease have shown dramatic improvements in the preliminary results of a small pilot study of a technique whereby a growth factor is pumped directly into dopamine deficient areas of the brain.

Neurologists working at the Frenchay Hospital in Bristol implanted catheters in the brains of five patients with Parkinson's disease (unilaterally affected, Hoehn and Yahr stage III; age range 46-62 years). The catheters were situated in the dorsal putamenthe region of the brain controlling movement that becomes deficient in the neurotransmitter dopamine in Parkinson's disease.

Two pumps in the anterior abdominal wall then continuously pumped glial derived neurotrophic factor, which is needed for the development of dopaminergic neurons, into the brain at a dosage of approximately 14µg/day. One of the researchers, Dr Steven Gill, consultant neurosurgeon at the Frenchay Hospital, explained: "We can deliver a drug very precisely to areas in the brain in the concentrations that we need to cause recovery, and we can control that very precisely."

The preliminary results showed marked improvement in the symptoms of Parkinson's disease in all five of the patients taking part in the pilot. The patients all improved in their ability to walk, and one patient regained his sense of smell. Patients improved across a wide range of measuresincluding the united Parkinson's disease rating scale (UPDRS), SF-36 (a quality of life scale), and timed motor tasks.

Dr Gill reported: "All patients were as good in their off state [when symptoms are at their most severe] as their preoperative on state. In their on state patients improved on the UPDRS by 44% In their off state they improved by 54% This level of improvement has not been seen with any other treatmentit is even better than the best results achieved with cell transplantation."

He was surprised at the speed of the effect. "We thought that this drug would take some months or years to be effective, but we found that really within a month or two patients were noticing significant changes."

The results were presented last week at the 54th annual meeting of the American Neurological Association, in Denver, Colorado, and will be published in the next few weeks. However, Dr Gill stressed that the results were preliminary and that it remains to be seen how long the improvements last and whether the treatment would suit all patients with Parkinson's disease.

Patients in the Bristol study are being scanned with positron emission tomography to assess whether the treatment achieves changes in the areas of the brain that have been damaged by the disease.

Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ FibroSleep™ Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Undenatured Type II Collagen - Chicken Soup for Your Joints Undenatured Type II Collagen - Chicken Soup for Your Joints
The Guaifenesin Story: A centuries-old bark extract used for clearing the airways – now key to a popular FM symptom-reversal protocol The Guaifenesin Story: A centuries-old bark extract used for clearing the airways – now key to a popular FM symptom-reversal protocol
Block Acid Reflux to Prevent Esophageal Problems! Block Acid Reflux to Prevent Esophageal Problems!
Strontium - The Missing Mineral for Strong Bones Strontium - The Missing Mineral for Strong Bones
Safely Burn Away Body Fat Safely Burn Away Body Fat

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map