ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Ultrasound Therapy for Fibromyalgia and Lyme Disease

Curcumin: The All In One Solution, Part 2

What Are the Benefits of Vitamin K2?

Vitamin D deficiency + high fat diet = metabolic syndrome

Why You Should Take Your Apple Cider Vinegar at Night

Use Burdock Oil to Promote Healthy Hair Growth

AMA journal associates iron deficiency with hearing loss

Meet Your Weight Loss Goals

People with forms of early-onset Parkinson's disease may benefit from boosting niacin in diet, resea...

Lutein linked to preservation of crystallized intelligence

 
Print Page
Email Article

Abstract: Fibromyalgia: a challenge for neuroscience

  [ 91 votes ]   [ Discuss This Article ]
www.ProHealth.com • July 7, 2003


Rev Neurol. 2003 Jun 16-30;36(12):1165-75.  [Article in Spanish]  Leza JC.  Universidad Complutense. Facultad de Medicina, Madrid, Espa a.

AIMS. In this survey we present the most recent findings regarding the physiopathology and therapeutic guidelines of a disease we still know very little about: fibromyalgia. This disorder is characterized by a chronic process of generalized musculoskeletal pain accompanied by chronic fatigue, sleep disorders and, on many occasions, neuroendocrine disorders.

DEVELOPMENT. Most research on the physiopathology of fibromyalgia points towards some kind of pain transmission disorder in the dorsal horn of the spinal cord. In chronic pain processes, a resonance effect is produced in the synapse of the dorsal horn and this gives rise to allodynia and hyperalgesia. From a biochemical point of view, glutamate and substance P receptors, as well as the main systems involved in the transmission of pain, serotonin and noradrenaline, seem to play a fundamental role. Patients with fibromyalgia have generally been seen to have lowered 5HT activity and an increase in substance P. In addition to these alterations in the perception of pain, serotonin could also be responsible for the frequently occurring sleep, hormone and neuropsychiatric disorders observed in these patients.

CONCLUSIONS. Nowadays fibromyalgia is still a challenge for modern medicine. Indeed, the neuroscientific community must design a basic scientific approach carried out at the patient s bedside in order to find pharmacological tools with which to relieve these symptoms. Of the extensive therapeutic arsenal that has been tested in these patients to date, classical antidepressants and serotonin and noradrenaline reuptake inhibitors, used in sub antidepressant doses, seem to be the most effective.

PMID: 12833238 [PubMed - in process]




Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Ultra ATP+, Double Strength Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products


Article Comments



Be the first to comment on this article!

Post a Comment


 
NAD+ Ignite with Niagen

Featured Products

Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Natural Support for Mood, Sleep and Mental Focus? L-theanine Natural Support for Mood, Sleep and Mental Focus? L-theanine
Vital Molecule Increases Cellular Energy and Improves Cognitive Function Vital Molecule Increases Cellular Energy and Improves Cognitive Function
Bone Broth Benefits for Digestion, Arthritis and Cellulite Bone Broth Benefits for Digestion, Arthritis and Cellulite
Restore Youthful Cognition and Well-Being Restore Youthful Cognition and Well-Being
Quercetin: Natural Support for Allergy & Inflammation Relief and More Quercetin: Natural Support for Allergy & Inflammation Relief and More

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map