ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

Fight Back! Win the War Being Waged Against Your Immune System

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Pumpkin Pie Turmeric Breakfast Smoothie - Vegan + Gluten-Free

Vitamin D supplementation extends life in mouse model of Huntington's disease

Omega-3 fatty acid stops known trigger of lupus

Conquer Your Email Inbox, Increase Productivity and Reduce Stress

Print Page
Email Article

The Use of D-Ribose in Chronic Fatigue Syndrome and Fibromyalgia: A Pilot Study

  [ 407 votes ]   [ 1 Comment ]
By J.E. Teitelbaum, et al. • • November 29, 2006

Journal: Journal of Alternative and Complementary Medicine. 2006 Nov;12(9):857-862.

Authors and affiliation: Teitelbaum JE, Johnson C, Cyr JS. Fibromyalgia and Fatigue Centers, Dallas, Texas, USA.

PMID: 17109576

Objectives: Fibromyalgia (FMS) and Chronic Fatigue Syndrome (CFS) are debilitating syndromes that are often associated with impaired cellular energy metabolism. As D-ribose has been shown to increase cellular energy synthesis in heart and skeletal muscle, this open-label uncontrolled pilot study was done to evaluate if D-ribose could improve symptoms in Fibromyalgia and/or Chronic Fatigue Syndrome patients.

Design: Forty-one (41) patients with a diagnosis of FMS and/or CFS were given D-ribose, a naturally occurring pentose carbohydrate, at a dose of 5 g t.i.d. for a total of 280 g. All patients completed questionnaires containing discrete visual analog scales and a global assessment pre- and post-D-ribose administration.

Results: D-ribose, which was well-tolerated, resulted in a significant improvement in all five visual analog scale (VAS) categories: energy; sleep; mental clarity; pain intensity; and well-being, as well as an improvement in patients' global assessment. Approximately 66% of patients experienced significant improvement while on D-ribose, with an average increase in energy on the VAS of 45% and an average improvement in overall well-being of 30% (p < 0.0001).

Conclusions: D-ribose significantly reduced clinical symptoms in patients suffering from Fibromyalgia and Chronic Fatigue Syndrome.

Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Ultra EPA  - Fish Oil Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments Post a Comment

re: pilot study
Posted by: Gerald Campbell PhD
Jul 3, 2012
I don't know if many people closely read this article (not just the abstract above), but I see one major flaw with it right away. They exclude anyone who has used D-ribose at any time in the past. By doing this they are excluding a significant patient population who has tried D-ribose previously and not responded; this could increase the proportion of patients responding and and average extent of response.

There was also no breakdown of how many responded, of CFS vs. FM (altho the raw data is present it is not analyzed or discussed), or of response vs. any of the other data they did (or should have) collected including how long the patient has been ill, age, sex, or any clinical lab tests.

In addition, they cite the "increase" in CFS prevalence without even a mention of the changes in definition and diagnostic criteria in the interim.

Overall, to me this seems more like a product-promotion study than a scientific one.

As a matter of full disclosure, I have CFS for nearly 20 years, and tried D-ribose without any success. I have no financial interest in Corvalen, nor any relationship with any of the authors.

Gerald R. Campbell, Ph.D.
Reply Reply
Natural Pain Relief Supplements

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health

Natural Remedies

The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health The Revolutionary 'Good Fat' That Promotes Heart, Brain, Bone and Joint Health
SAD? Coping with Seasonal Affective Disorder SAD? Coping with Seasonal Affective Disorder
Repair Damaged Mitochondria and Reduce Fatigue Up to 45% Repair Damaged Mitochondria and Reduce Fatigue Up to 45%
Physically and Mentally Exhausted? How to Restore Energy at Its Source Physically and Mentally Exhausted? How to Restore Energy at Its Source
Secret Nutrient for Radiant Skin Secret Nutrient for Radiant Skin

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map