ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

On-and-off fasting helps fight obesity, study finds

Can Pomegranates Slow Aging?

Calorie restriction promotes longevity through effects on mitochondrial network

Discover Why Ashwagandha Can Be Used for Stress and Anxiety

How Can You Benefit From Vitamin B12?

A spoonful of oil: Fats and oils help to unlock full nutritional benefits of veggies, study suggests

Lower magnesium levels linked with increased mortality risk during up to 40 years of follow-up

Higher resveratrol dose linked to lower glucose levels in type 2 diabetics

What Is Bitter Orange?

Drug can dramatically reduce weight of people with obesity

 
Print Page
Email Article

Post-radiation syndrome as a NO/ONOO(-) cycle, chronic fatigue syndrome-like disease - Source: Medical Hypotheses, Jul 29, 2008

  [ 43 votes ]   [ Discuss This Article ]
By Martin L. Pall, PhD • www.ProHealth.com • August 4, 2008


[Note: The full text of this article is available on the Co-Cure listserv site.]

Post-radiation syndrome is proposed to be chronic fatigue syndrome (CFS) or a chronic fatigue syndrome-like illness, initiated by exposure to ionizing radiation.

This view is supported by the nitric oxide/peroxynitrite (NO/ONOO(-)) cycle mechanism, the putative etiologic mechanism for CFS and related illnesses.*

Ionizing radiation may initiate illness by increasing nitric oxide levels via increased activity of the transcription factor NF-kappaB and consequent increased synthesis of the inducible nitric oxide synthase.

[Some sources of ionizing radiation include X-rays, gamma rays, radon, atomic weapons test fallout. Types of radiant energy that are not ionizing include microwaves, radio waves, UV light and visible light, according to the World Health Organization.]

Two types of components of the nitric oxide/peroxynitrite cycle have been studied in post-radiation syndrome patients and shown to be elevated. The symptoms and signs of post-radiation syndrome and its chronicity are similar or identical to those of chronic fatigue syndrome and can be explained as being a consequence of nitric oxide/peroxynitrite cycle etiology.

While the data available to test this view are limited, it provides for the first time a comprehensive explanation for post-radiation syndrome.

Source: Medical Hypotheses, July 29, 2008. [E-pub ahead of print] PMID: 18667279, by Pall ML. School of Molecular Biosciences, Washington State University, Pullman, Washington, USA. [E-mail: martin_pall@wsu.edu]
___
* For information on the NO/ONOO(-) cycle, see "Nitric Oxide Cycle Theory: Will It Explain CFS, FM, and Other ‘Unexplained’ Illnesses? - Q&A with Martin L. Pall, PhD". Dr. Pall is author of the groundbreaking book, Explaining Unexplained Illnesses.





Post a Comment

Featured Products From the ProHealth Store
Energy NADH™ 12.5mg Vitamin D3 Extreme™ Optimized Curcumin Longvida®


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol The Most Powerful Natural Antioxidant Discovered to Date - Hydroxytyrosol
Breaking Through the Mental Fog Breaking Through the Mental Fog
Joint Aches May Have Met Their Match in Curcumin Joint Aches May Have Met Their Match in Curcumin
Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial
Can Pomegranates Slow Aging? Can Pomegranates Slow Aging?

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map