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Vitamin D and mood disorders among women: An integrative review - Source: Journal of Midwifery and Women’s Health, Sep-Oct 2008

  [ 114 votes ]   [ 6 Comments ]
By PK Murphy, CL Wagner • • November 9, 2008

This integrative review evaluates research studies that investigated the association between vitamin D and mood disorders affecting women to determine whether further research comparing these variables is warranted. A literature search using CINAHL, PsycINFO, MEDLINE, and PubMed databases was conducted to locate peer-reviewed mood disorder research studies that measured serum 25-hydroxyvitamin D (25[OH]D) levels.

Four of six studies reviewed imparted significant results, with all four showing an association between low 25(OH)D levels and higher incidences of four mood disorders:

• Premenstrual syndrome,

• Seasonal affective disorder,

• Non-specified mood disorder,

• And major depressive disorder.

This review indicates a possible biochemical mechanism occurring between vitamin D and mood disorders affecting women, warranting further studies of these variables using rigorous methodologies.

Source: Journal of Midwifery and Women’s Health, Sep-Oct 2008; 53(5):440-6. PMID: 18761297, by Murphy PK, Wagner CL. Medical University of South Carolina, Charleston, South Carolina, USA. [E-mail:]

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Article Comments Post a Comment

Sources Of Vitamin D for women who wanna know.
Posted by: GaDiE
Nov 12, 2008
1- Exposure to sunlight: Its an important source of vitamin D, Ultraviolet (UV) rays from sunlight trigger vitamin D synthesis in the skin. SO THATS WHY THEY SAY THAT SUN IS A NTURAL ANTIDEPRESSANT according to this research. 2- Food sources of vitamin D: Cod Liver Oil, 1 Tbs: 1,360 IU Salmon, cooked, 3 1/2 oz: 360 IU Mackerel, cooked, 3 1/2 oz: 345 IU Sardines, canned in oil, drained, 3 1/2 oz: 270 IU Milk, nonfat, reduced fat, and whole, vitamin D fortified, 1 c: 98 IU Margarine, fortified, 1 Tbs: 60 IU Pudding, 1/2 c prepared from mix and made with vitamin D fortified milk: 50 IU Dry cereal, Vitamin D fortified w/10% of the recommended daily value, 3/4 c: 40-50 IU (other cereals may be fortified with more or less vitamin D) Liver, beef, cooked, 3 1/2 oz: 30 IU Egg, 1 whole (vitamin D is present in the yolk): 25 IU
Reply Reply

good forms of Vit D
Posted by: Sandy10m
Nov 13, 2008
If you don't go into the sun because of skin cancer or the threat of it, then you need to take a Vit D supplement. The most bioavailable form is D3 Cholecalciferol. By the way, milk contains only a small amount of D3 compared to what you need for maximum health (and not the RDA, which will only keep you from getting rickets and nothing more). You also need an adequate intake of cholesterol too. That's right, the stuff that MD doctors tell us to avoid like the plague. If your cholesterol count is below 180, you may not be giving your body enough cholesterol to make all the hormones in your body. Without hormones (and I'm not just talking about the sex hormones that we normally think of), we die. It's that simple. And D3 is essential for the repair of bone with calcium. Without enough D3, your body doesn't use calcium properly. I hope that helps.
Reply Reply

Vitamin D as an antidepressant
Posted by: Susie14
Dec 9, 2008
I have been taking Cod Liver Oil capsules for many years now and if I run out & don't replace them promptly it is only a matter of days before my mood drops considerably.Initially I took them as a simple and inexpensive supplement. Now I know that my body was leading me well & even though, living in NZ I get plenty of sunshine, that extra Vit D & A is critical to improving my mood.I have ME & Fibromyalgia.
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50,000 iu of vitamin D???
Posted by: skikat
Dec 26, 2008
i have fibro and many other things that i have to deal with along with osteoporosis. last week my doctor put me on 50,000 I.U. of vitamin D 3 to be taken every sunday. i had never heard of such a high dose and was scared to take it . after a few days, i gave in and i have taken my first dose 2 days ago. has anyone else ever heard of taking that high a dose ? and why -once a week? please respond. thanks. ski
Reply Reply

50,000 IU Vitamin D
Posted by: DebMasters
Jan 16, 2009
I was diagnosed with fibromyalgia about 3 mos. ago and my vitamin D was also tested and found that it was low...I am also taking 50,000 IU once a week...I think it might be helping just a little bit.


Vitamin D 50,000 units
Posted by: krisz
Feb 1, 2009
After testing my Vitamin D levels, my dr. prescribed 50,000 once a week, for about 6 mo. Then my levels will be tested again. After a couple of months, I think this helped me feel better. I have a friend whose dr. prescribed 50,000 D twice a week for several months.
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