ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

Fight Back! Win the War Being Waged Against Your Immune System

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Pumpkin Pie Turmeric Breakfast Smoothie - Vegan + Gluten-Free

Vitamin D supplementation extends life in mouse model of Huntington's disease

Omega-3 fatty acid stops known trigger of lupus

Conquer Your Email Inbox, Increase Productivity and Reduce Stress

Print Page
Email Article

POTS symptoms generally more severe in CFS patients, Vanderbilt finds

  [ 12 votes ]   [ Discuss This Article ] • September 14, 2011

Neurohumoral and Hemodynamic Profile in Postural Tachycardia and Chronic Fatigue Syndromes
– Source: Clinical Science, Sep 12, 2011

By Luis E Okamoto, Italo Biaggioni, et al.

Several studies recognized an overlap between chronic fatigue (CFS) and postural tachycardia (POTS) syndromes.

We compared the autonomic and neurohormonal phenotype of POTS patients with CFS (CFS-POTS) to those without CFS (non-CFS POTS), to determine whether CFS-POTS represents a unique clinical entity with a distinct pathophysiology.

We recruited 58 patients with POTS, of which 47 were eligible to participate: 93% of them reported severe fatigue (Checklist Individual Strength [CIS], fatigue subscale <36), and 64% (n=30) fulfilled criteria for CFS (CFS-POTS).

• The prevalence of CFS symptoms (Centers for Disease Control and Prevention criteria) was greater in the CFS-POTS group

• But the pattern of symptoms was similar in both groups.

• Physical functioning was low in both groups (RAND-36 Health Survey, 40±4 vs. 33±3, p=0.153),

• Despite more severe fatigue in CFS-POTS patients (CIS fatigue subscale 51±1 vs. 43±3, p=0.016).

• CFS-POTS patients had:

- Greater orthostatic tachycardia than the non-CFS POTS group (51 +/- 3 vs. 40 +/- 4 bpm, p=0.030),

- Greater low frequency variability of blood pressure (6.3+/-0.7 vs. 4.8+/-1.0 mmHg2, p=0.019),

- Greater BP recovery from early to late phase II of the Valsalva maneuver (18+/-3 vs. 11+/-2 mmHg, p=0.041),

- And a higher supine (1.5+/-0.2 vs. 1.0+/-0.3 ng/mL/h; p=0.033) and upright (5.4+/-0.6 vs. 3.5+/-0.8 ng/mL/h; p=0.032) plasma renin activity.

In conclusion:

• Fatigue and CFS-defining symptoms are common in POTS patients. The majority of them met criteria for CFS.

• CFS-POTS patients have higher markers of sympathetic activation but are part of the spectrum of POTS.

• Targeting this sympathetic activation should be considered in the treatment of these patients.

Source: Clinical Science, Sep 12, 2011. DOI:doi:10.1042/CS20110200 by Okamoto LE, Raj SR, Peltier AC, Gamboa A, shibao CA, Dierich A, Black BK, Robertson D, Biaggioni I. Vanderbilt University School of Medicine, Nashville, Tennessee, USA. [Email:]

Post a Comment

Featured Products From the ProHealth Store
Vitamin D3 Extreme™ Ultra ATP+, Double Strength Mitochondria Ignite™ with NT Factor®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Priming Your Immune System for Cold & Flu Season Priming Your Immune System for Cold & Flu Season
Why Berries Offer a Rainbow of Health Benefits Why Berries Offer a Rainbow of Health Benefits
Thyroid Health and Fibromyalgia Thyroid Health and Fibromyalgia
Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt Cocoa's Polyphenol Riches - All the Health Benefits without the Sugar, Calories or Guilt
Relief for Dry, Itchy Skin Caused by Fibromyalgia Relief for Dry, Itchy Skin Caused by Fibromyalgia

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map