ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

16 Tips from 16 Years Sick

Fibromyalgia Fare Fit for All Seasons

Tangerine Oil: A Citrusy Essential Oil With Well-Rounded Uses

New Study Shows Artificial Sweeteners Lead to Diabetes

Essential Oils — An Effective and Healthy Option to Treat Headaches

Antioxidant treatment could halt neurodegeneration in early Parkinson's

Higher vitamin D levels associated with less severe disease in NAFLD patients

How zinc helps fight esophageal cancer

Krill Oil: Make This Omega-3 Supplement Part of Your Health Regimen

Everything You Need to Know About Black Cohosh

 
Print Page
Email Article

A Nasal Vaccine for Alzheimer's Disease?

  [ 369 votes ]   [ Discuss This Article ]
www.ProHealth.com • August 15, 2005


By Miranda Hitti (WebMD) So far, the vaccine has only been tested on mice, not people. "It works in mice," researcher Howard Weiner, MD, tells WebMD. "I think the significance of the experiment is we've discovered a unique way of vaccination that may be of help for Alzheimer's. "We think it's very exciting. The next step is to see whether it's safe in humans and then we can test to see how efficacious it is," says Weiner. He is the co-director of the Center for Neurologic Diseases at Boston's Brigham and Women's Hospital and Harvard Medical School, and the director of the Partners Multiple Sclerosis Center at Brigham and Women's Hospital. Results of vaccine tests on mice appear in The Journal of Clinical Investigation. Vaccine's Ingredients The vaccine mixes an FDA-approved multiple sclerosis [MS] drug and an additional substance that helps the vaccine stimulate immunity. The nasal vaccination can be given as a spray or as drops. Drops were used on the mice in Weiner's study. Read WebMD's "Memory Lapses: Are They Normal?" Study's Results The study focused on mice with an Alzheimer's-like brain disease. The mice got vaccine treatments and boosters for several weeks. The vaccine is designed to activate brain cells called microglia. The microglia, in turn, are supposed to clean up a protein called beta-amyloid, which is found in brain plaques seen in Alzheimer's disease. After the nasal vaccine treatments, total beta-amyloid levels dropped 73 perent, write the researchers. Read WebMD's "New Thinking About Alzheimer's Treatment" Surprise Discovery Why did Weiner's team decide to make a nasal vaccine from those particular drugs? They had been trying to figure out why another Alzheimer's vaccine hadn't worked. That vaccine had directly targeted beta-amyloid with antibodies, but side effects stopped trials of that vaccine in people. "During that time, we made the unexpected discovery that if we gave the animals a type of disease that's like MS [multiple sclerosis], it cleared 80 perent of the beta [amyloid] from the brain. And when we made that discovery, the question was, how is this happening and can we take the discovery and find a way to use it to come up with a new vaccine for Alzheimer's," says Wiener. The nasal vaccine doesn't stimulate the body to make antibodies. "In fact, in the animal models, it worked in mice that are genetically unable to make antibodies, so it's a totally unique type of vaccine from all the other vaccines that have been tried," says Weiner. Beta-amyloid deposits are a bit different in mice and people, and the vaccine's long-term results aren't known yet, write the researchers. Another researcher who worked on the study is an employee of and has shares in ID Biomedical Corporation of Quebec, the nasal treatment's maker, the journal notes. Read WebMD's "Healthy Gums May Help Fight Alzheimer's" By Miranda Hitti, reviewed by Brunilda Nazario, MD SOURCES: Frenkel, D. The Journal of Clinical Investigation, Aug. 11, 2005; online edition. Howard Weiner, MD, co-director, Center for Neurologic Diseases, Brigham and Women's Hospital/Harvard Medical School; director, Partners Multiple Sclerosis Center, Brigham and Women's Hospital. News release, The Journal of Clinical Investigation.



Post a Comment

Featured Products From the ProHealth Store
Ultra ATP+, Double Strength Mitochondria Ignite™ with NT Factor® Ultra EPA  - Fish Oil


Article Comments



Be the first to comment on this article!

Post a Comment


 
Optimized Curcumin Longvida with Omega-3

Featured Products

FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Optimized Curcumin Longvida® Optimized Curcumin Longvida®
Supports Cognition, Memory & Overall Health
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function

Natural Remedies

SAD? Coping with Seasonal Affective Disorder SAD? Coping with Seasonal Affective Disorder
Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing Rejuvenating the Brain - How PQQ Helps Power Up Mental Processing
Secret Nutrient for Radiant Skin Secret Nutrient for Radiant Skin
Guarding Against the Dangers of Vitamin D Deficiency Guarding Against the Dangers of Vitamin D Deficiency
The Big Blue Fish that Helps Chase the Blues Away The Big Blue Fish that Helps Chase the Blues Away

CONTACT US
ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
SHOP WITH CONFIDENCE
Credit Card Processing
SUBSCRIBE TO OUR NEWSLETTERS
Get the latest news about Fibromyalgia, M.E/Chronic Fatigue Syndrome, Lyme Disease and Natural Wellness

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2017 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map