ProHealth me-cfs Vitamin and Natural Supplement Store and Health
Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help

|
|

Trending News

The Cheney Protocol for Chronic Fatigue Syndrome

Is the physical examination normal in CFS?

Traditional Chinese medicine for chronic fatigue syndrome: A systematic review of randomized clinica...

Burmeister Wins Lawsuit: Court Rules Government Must Produce IOM Documents

Symptoms of autonomic dysfunction in chronic fatigue syndrome

Your Rights When a Disability Claim is Terminated

From Our Readers: Comments & Suggestions – 9/10/14

Overcoming the barriers to the diagnosis and management of chronic fatigue syndrome/ME in primary ca...

Is The Physical Examination Normal in CFS? Part 2: Joint Hypermobility

Treating Immune Dysfunction in ME/CFS

 
Print Page
Email Article

Latent viral immune inflammatory response model for chronic multisymptom illness – Source: Medical Hypotheses, Dec 20, 2012

  [ 56 votes ]   [ Discuss This Article ]
By Sean R Maloney, Paula Goolkasian, et al. • www.ProHealth.com • December 27, 2012


A latent viral immune inflammatory response (LVIIR) model is presented which integrates factors that contribute to chronic multisymptom illness (CMI) in both the veteran and civilian populations.

The LVIIR model for CMI results from an integration of clinical experience with a review of the literature in four distinct areas:

1. Studies of idiopathic multisymptom illness in the veteran population including two decades of research on Gulf War I veterans with CMI,

2. New evidence supporting the existence of chronic inflammatory responses to latent viral antigens and the effect these responses may have on the nervous system,

3. Recent discoveries concerning the role of vitamin D in maintaining normal innate and adaptive immunity including suppression of latent viruses and regulation of the immune inflammatory response, and

4. The detrimental effects of extreme chronic repetitive stress (ECRS) on the immune and nervous systems.

The LVIIR model describes the pathophysiology of a pathway to CMI and presents a new direction for the clinical assessment of CMI that includes the use of neurological signs from a physical exam, objective laboratory data, and a new proposed latent viral antigen-antibody imaging technique for the peripheral and central nervous system.

The LVIIR model predicts that CMI can be treated by a focus on:

• Reversal of immune system impairment,

• Suppression of latent viruses and their antigens,

• And healing of nervous system tissue damaged by chronic inflammation associated with latent viral antigens and by ECRS.

In addition, the LVIIR model suggests that maintaining optimal serum 25 OH vitamin D levels will maximize immune system suppression of latent viruses and their antigens and will minimize immune system inflammation.

This model also emphasizes the importance of decreasing ECRS to improve immune system function and to minimize nervous system injury from excess serum glucocorticoid levels.

The proposed model supports growing evidence that increasing omega 3 essential fatty acid levels in nervous system tissues may decrease inflammation in the nervous system and improve neural plasticity and recovery from neuronal injury.

Source: Medical Hypotheses, Dec 20, 2012. Maloney SR, Jensen S, Gil-Rivas V, Goolkasian P. Deployment Processing Command-EAST, Camp Lejeune, NC; Hefner VA Medical Center, Salisbury, NC; University of North Carolina, Charlotte, NC. [Email: pagoolka@uncc.edu]




Please Discuss This Article:   Post a Comment 



[ Be the first to comment on this article ]




 
Free Chronic Fatigue Syndrome and Fibromyalgia Newsletters
Subscribe to
Our FREE
Newsletter
Subscribe Now!
Receive up-to-date ME/CFS & Fibromyalgia treatment and research news
 Privacy Guaranteed  |  View Archives

Free Shipping on Nutritional Supplement Orders

Featured Products

MitoQ® MitoQ®
Powerful Antioxidant Support to Mitochondria
B-12 Extreme™ B-12 Extreme™
The Most Potent Vitamin B-12 on Earth
Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
Hydroxocobalamin Extreme™ Hydroxocobalamin Extreme™
The B-12 your brain needs for detox & sharpness

Natural Remedies

A Breakthrough for Mitochondrial Dysfunction A Breakthrough for Mitochondrial Dysfunction
Could a B-12 Deficiency Be Causing Your Symptoms? Could a B-12 Deficiency Be Causing Your Symptoms?
Green Coffee Extract: Unique Obesity Intervention Green Coffee Extract: Unique Obesity Intervention
Shoo Pain, Don't Bother Me - Top 10 Nutrients to Take Back Your Life Shoo Pain, Don't Bother Me - Top 10 Nutrients to Take Back Your Life
Dreaming of a Good Night's Sleep? Dreaming of a Good Night's Sleep?

FIBROMYALGIA RESOURCES
What is Fibromyalgia?
Fibromyalgia 101
Fibromyalgia Symptoms
Fibromyalgia Treatments
| CFS RESOURCES
What is CFS?
ME/CFS 101
ME/CFS Symptoms
ME/CFS Treatments
| FORUMS
Fibromyalgia
ME/CFS
ADVANCED MEDICAL LABS
WHOLESALE  |  AFFILIATES
GUARANTEE
CONTACT US
PRIVACY
RSS
SITE MAP
ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus
Credit Card Processing