ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

Fight Back! Win the War Being Waged Against Your Immune System

The role of microbiota and intestinal permeability in the pathophysiology of autoimmune and neuroimm...

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Acupressure reduced fatigue in breast cancer survivors

Omega-3 fatty acid stops known trigger of lupus

What’s Fenugreek Good For?

Print Page
Email Article

Professional exposure to pesticides and Parkinson’s disease – Source: Annals of Neurology, Apr 13, 2009

  [ 17 votes ]   [ Discuss This Article ]
By Alexis Elbaz, MD, PhD, et al. • • June 4, 2009

[Note: the organochlorine insecticides that this study of farmers implicates particularly in Parkinson’s are very persistent in the environment and the body. DDT is one of them.]

Objective: We studied the relation between Parkinson's disease (PD) and professional exposure to pesticides in a community-based case-control study conducted in a population characterized by a high prevalence of exposure. Our objective was to investigate the role of specific pesticide families and to perform dose-effect analyses.

Methods: PD cases (n=224) from the Mutualite Sociale Agricole (MSA, France) were matched to 557 controls free of PD affiliated to the same health insurance. Pesticide exposure was assessed using a two-phase procedure, including a case-by-case expert evaluation. Analyses of the relation between PD and professional exposure to pesticides were first performed overall and by broad category (insecticides, fungicides, herbicides). Analyses of 29 pesticide families defined based on a chemical classification were restricted to men. Multiple imputation was used to impute missing values of pesticide families. Data were analyzed using conditional logistic regression, both using a complete-case and an imputed dataset.


• We found a positive association between PD and overall professional pesticide use (OR=1.8, 95% CI=1.1-3.1), with a dose-effect relation for the number of years of use (p=0.01).

• In men, insecticides were associated with PD (OR=2.2, 95% CI=1.1-4.3), in particular organochlorine insecticides (OR=2.4, 95% CI=1.2-5.0). [Note: an odds ratio of 1.0 would indicate no difference in odds of PD. An OR of 2.4 indicates the men who had used organochlorines were 140% more likely to develop Parkinson's on average.]

• These associations were stronger in men with older onset PD than in those with younger onset PD and were characterized by a dose effect relation in the former group.

Interpretation: Our results lend support to an association between PD and professional pesticide exposure and show that some pesticides (i.e., organochlorine insecticides) may be more particularly involved.

Source: Annals of Neurology, online Apr 13, 2009. DOI 10.1002/ana.21717, by Elbaz A, Clavel J, Rathouz PJ, Moisan F, Galanaud J, Delemotte B, Alperovitch A, Tzourio C. INSERM, Paris and Villejuif; UPMC University Paris, Paris and Villejuif; Mutualite Sociale Agricole, Bagnolet, France; Department of Health Studies, University of Chicago, Illinois, USA. [E-mail:]

Post a Comment

Featured Products From the ProHealth Store
FibroSleep™ Energy NADH™ 12.5mg Optimized Curcumin Longvida®

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Ultra ATP+, Double Strength Ultra ATP+, Double Strength
Get energized with malic acid & magnesium
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

The Remarkable Benefits of Reishi Medicinal Mushrooms The Remarkable Benefits of Reishi Medicinal Mushrooms
Live Without Anxiety or Stress Live Without Anxiety or Stress
Fatigue & Fibro Fog: Could You Have a B-12 Deficiency? Fatigue & Fibro Fog: Could You Have a B-12 Deficiency?
Health Benefits Are Brewing in Green Tea Health Benefits Are Brewing in Green Tea
Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial Mitochondria-Booster NIAGEN® Shows Promise in First Human Clinical Trial

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map