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BREAKING NEWS: FDA & NIH confirm WPI team’s XMRV & CFS findings! Paper on hold given conflicting CDC findings

  [ 148 votes ]   [ 5 Comments ] • June 22, 2010

“We (FDA & NIH) have independently confirmed the Lombardi group findings." -  Dr. Harvey Alter, National Institutes of Health

[Note: In further breaking news as of June 30, the Department of Health & Human Services has asked for a hold on the upcoming FDA & NIH article, owing to another paper set for publication by the CDC, claiming their researchers failed to confirm the Lombardi-Mikovits findings. (This paper is also now on hold). The NIH wants an explanation of the day & night discrepancy among three leading US scientific agencies. See today's Wall Street Journal article, "Chronic Fatigue [Syndrome] Link to Virus Disputed" by Amy Docker Marcus.]

Gendringen, the Netherlands, Jun 22 - The FDA and the NIH have independently confirmed the XMRV findings as published in Science, October last.

This confirmation was issued by Dr. Harvey Alter of the NIH during a closed workshop on blood transfusion held on May 26-27 in Zagreb.

Two journalists from the Dutch magazine for health professionals, ORTHO, who have been working on XMRV stories for several months, were able to obtain a copy of the Alter lecture.

In the October 8, 2009 issue of Science Express, the Lombardi-Mikovits group at the Whittemore Peterson Institute (WPI), the Cleveland Clinic, and the National Cancer Institute (NCI) reported that 67% of 101 chronic fatigue syndrome (CFS) patients tested positive for infection with xenotropic murine retrovirus (XMRV). Only 3.7% of 218 healthy subjects tested were positive for this gammaretrovirus.

Since that time, a number of research groups have proved unable to independently confirm these findings.

On Friday last (June 18, 2010), the AABB [formerly American Association of Blood Banks, now with members in 80 countries] released an Association Bulletin recommending that its member blood collectors actively discourage potential donors who have been diagnosed with CFS from donating blood or blood components.

This interim measure was proposed by the AABB Interorganizational Task Force on XMRV. This Task Force includes representatives from several government agencies, including the Center for Disease Control and Prevention (CDC), the Food and Drug Administration (FDA) and the National Institutes of Health (NIH). The fact that the measure was introduced suggests the presence of information not yet published.

The ORTHO journalists were able to obtain a pdf document of the lecture given by Harvey Alter at the IPFA/PEI 17th Workshop on 'Surveillance and Screening of Blood Borne Pathogens” in Zagreb. The International Plasma Fractionation Association (IPFA) represents the not-for-profit organizations around the world involved in plasma fractionation. The IPFA is based in Amsterdam, the Netherlands.

The highly-experienced Dr. Harvey Alter is Clinical Studies Chief at the Infectious Diseases and Immunogenetics Section of the Department of Transfusion Medicine at the NIH Clinical Center in Bethesda, Maryland.

• "The data in the Lombardi, et al. Science manuscript are extremely strong and likely true, despite the controversy," was one comment on the XMRV findings reported by Alter in Zagreb.

"Although blood transmission to humans has not been proved, it is probable.

"The association with CFS is very strong, but causality not proved.

"XMRV and related MLVs are in the donor supply with an early prevalence estimate of 3% to 7%."

"We (FDA & NIH) have independently confirmed the Lombardi group findings."

ORTHO contacted Dr. Harvey Alter today for a reaction. He did not want to comment, but confirmed that a paper is soon to be published.

[Ed Note: See also Hillary Johnson's blog ("THE BIG ONE, June 21, 2010") stating she's learned by the grapevine that an article now in press at "a highly respected journal" may provide new, "even stronger" data connecting XMRV with ME/CFS than the Mikovits article. Hillary wrote the notable book, Osler's Web.]

Source: ORTHO news release, June 22, 2010. ORTHO is a Dutch magazine for health professionals focusing on nutrition and dietary supplements, based in Gendringen, the Netherlands. ORTHO has been publishing reports on CFS since 1988. Editor-in-chief: Gert E. Schuitemaker (PhD). Tel: + 31 (0) 315 695211 + 31 (0) 315 695211 / + 49 (0) 170 808 9484 + 49 (0) 170 808 9484. E-mail:

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Article Comments Post a Comment

Now THIS is exciting news!!
Posted by: UncleChief
Jun 22, 2010
Positive thinking everyone!! Love X
Reply Reply

Posted by: Juloo
Jun 22, 2010
Good work!
Reply Reply

What of the Herpes
Posted by: IanH
Jun 23, 2010
Martin Lerner's blood samples from their cohort should be tested for XMRV before and after treatment. If the people who were successfully treated have XMRV in their blood after successful treatment, what does this tell us about XMRV's or the Herpes virus' role in CFS. Aslo would be useful to know what the active Herpes viridae loads are in those WPI and now NIH samples tested for XMRV.
Reply Reply

Have been very interested in Lerner and also in EBV connection
Posted by: McCormick
Jun 29, 2010
I still think as I have since 1989 that the EBV connection and maybe Herpes 1, 2, 6, etc. cannot be ignored. Have not been to Lerner but considering going as last chance option.


still waiting
Posted by: moineau
Jul 13, 2010
july 13th, the cdc paper is out, isn't that a surprise that they'd print their invalidated study first! bring out the fda/nih paper now! (you frauds)
Reply Reply

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