ProHealth health Vitamin and Natural Supplement Store and Health
Home  |  Log In  |  My Account  |  View Cart  View Your ProHealth Vitamin and Supplement Shopping Cart
800-366-6056  |  Contact Us  |  Help
Facebook Google Plus
Fibromyalgia  Chronic Fatigue Syndrome & M.E.  Lyme Disease  Natural Wellness  Supplement News  Forums  Our Story
Store     Brands   |   A-Z Index   |   Best Sellers   |   New Products   |   Deals & Specials   |   Under $10   |   SmartSavings Club

Trending News

Fight Back! Win the War Being Waged Against Your Immune System

10 Fibro-Friendly Foods with a Bonus: Beautiful Skin

The role of microbiota and intestinal permeability in the pathophysiology of autoimmune and neuroimm...

Studies Show that Magnesium L-threonate Improves Brain Plasticity, Leading to Direct and Significant...

Clary Sage Oil May Be Pricey, but Its Benefits Are Priceless

Component of red wine, grapes can help to reduce inflammation, study finds

Poly MVA: A Novel Therapy for Increasing Energy, Repairing DNA, and Promoting Overall Health

Acupressure reduced fatigue in breast cancer survivors

Omega-3 fatty acid stops known trigger of lupus

What’s Fenugreek Good For?

Print Page
Email Article

Prevalence of ME/CFS in England - roughly 2 in 1,000 primary care patients ages 18-64

  [ 11 votes ]   [ Discuss This Article ] • July 29, 2011

Prevalence of myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) in three regions of England: A repeated cross-sectional study in primary care – Source: BMC Medicine, Jul 28, 2011

By Luis C Nacul, et al.

[Note: The research reported here was conducted in 2010, so did not address prevalence of cases according to the International Consensus Criteria (ICC) for diagnosis of Myalgic Encephalomyelitis, published in July 2011. But this study did calculate prevalence according to the Canadian Consensus Criteria, which influenced the ICC. Overall, prevalence was higher in women, varied by area and among the different sets of diagnostic criteria used; but average incidence according to any set of criteria considered was 2 in 1,000 primary care patients ages 18-64. To read the full text pdf of this article, click here -]


Background: ME/CFS or chronic fatigue syndrome (CFS) has been used to name a range of chronic conditions characterized by extreme fatigue and other disabling symptoms. Attempts to estimate the burden of disease have been limited by selection bias, and by lack of diagnostic biomarkers and of agreed reproducible case definitions.

We estimated the prevalence and incidence of ME/CFS in three regions in England, and discussed the implications of frequency statistics and the use of different case definitions for health and social care planning and for research.

Methods: We compared the clinical presentation, prevalence and incidence of ME/CFS based in a sample of 143,000 individuals aged 18 to 64 years, covered by primary care services in 3 regions of England.

Case ascertainment involved:

1. Electronic search for chronic fatigue cases;

2. Direct questioning of general practitioners (GPs) on cases not previously identified by the search;

3. Clinical review of identified cases according to:

• CDC-1994,

• Canadian

• And Epidemiological Case (ECD) Definitions.

This enabled the identification of cases with high validity.

Results: The estimated minimum prevalence rate of ME/CFS was:

• 0.2% [2 cases per 1,000 primary care patients ages 18-64] for cases meeting any of the study case definitions,

• 0.19% for the CDC-1994 definition [1.9 cases per 1,000],

• 0.11% for the Canadian definition [1.1 cases per 1,000]

• And 0.03% for the ECD [0.3 cases per 1,000].

The overall estimated minimal yearly incidence was 0.015% [minimum risk of ME/CFS in a given year, 1.5 cases in 10,000].

The highest rates were found in London and the lowest in East Yorkshire.

All cases conforming to the Canadian criteria also met the CDC-1994 criteria but presented higher prevalence and severity of symptoms.


• ME/CFS is not uncommon in England and represents a significant burden to patients and society.

• The number of people with chronic fatigue who do not meet specific criteria for ME/CFS is higher still.

• Both groups have high levels of need for service provision, including health and social care.

• We suggest combining the use of both the CDC-1994 and Canadian criteria for ascertainment of ME/CFS cases, alongside careful clinical phenotyping of study participants.

This combination if used systematically will enable international comparisons, minimization of bias, and the identification and investigation of distinct sub-groups of patients with possibly distinct aetiologies and pathophysiologies, standing a better chance of translation into effective specific treatments.

Source: BMC Medicine, Jul 28, 2011;9(91). DOI:10.1186/1741-7015-9-91, by Nacul LC, Lacerda EM, Pheby d, Campion P, Molokhia M, Fayyaz s, Leite JCDC, Poland F, Howe A, Drachler ML. Department of Nutrition and Public Health Interventions Research, London School of Hygiene and Tropical Medicine, London; Foundation for Genomics and Population Health, Cambridge; National ME Observatory Project & Bucks New University, High Wycombe, Buckinghamshire; Hull-York Medical School, University of Hull, Hull; Department of Primary Care and Public Health Sciences, Division of Health and Social Care Research. Kings College, London; University of East Anglia, Norwich, UK. [Email:]

Post a Comment

Featured Products From the ProHealth Store
Optimized Curcumin Longvida® Ultra EPA  - Fish Oil Energy NADH™ 12.5mg

Looking for Vitamins, Herbs and Supplements?
Search the ProHealth Store for Hundreds of Natural Health Products

Article Comments

Be the first to comment on this article!

Post a Comment

Natural Pain Relief Supplements

Featured Products

Energy NADH™ 12.5mg Energy NADH™ 12.5mg
Improve Energy & Cognitive Function
Ultra EPA  - Fish Oil Ultra EPA - Fish Oil
Ultra concentrated source of essential fish oils
Mitochondria Ignite™ with NT Factor® Mitochondria Ignite™ with NT Factor®
Reduce Fatigue up to 45%
Vitamin D3 Extreme™ Vitamin D3 Extreme™
50,000 IU Vitamin D3 - Prescription Strength
FibroSleep™ FibroSleep™
The All-in-One Natural Sleep Aid

Natural Remedies

Vitamin K-2 – A Key Player in Cardiovascular and Bone Health Vitamin K-2 – A Key Player in Cardiovascular and Bone Health
Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value Olea25 Olive Hydroxytyrosol Hits Astonishing 68,000+ ORAC Antioxidant Value
Breaking Through the Mental Fog Breaking Through the Mental Fog
Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep? Can Glycine + Amino Acids Be the Secret to Deep, Rejuvenating Sleep?
The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS The Crucial Role CoQ10 Plays in Fibromyalgia and ME/CFS

ProHealth, Inc.
555 Maple Ave
Carpinteria, CA 93013
(800) 366-6056  |  Email

· Become a Wholesaler
· Vendor Inquiries
· Affiliate Program
Credit Card Processing
Be the first to know about new products, special discounts and the latest health news. *New subscribers only

CONNECT WITH US ProHealth on Facebook  ProHealth on Twitter  ProHealth on Pinterest  ProHealth on Google Plus

© 2016 ProHealth, Inc. All rights reserved. Pain Tracker App  |  Store  |  Customer Service  |  Guarantee  |  Privacy  |  Contact Us  |  Library  |  RSS  |  Site Map