Researchers discovered differences between mildly and severely reactive astrocytes, which may explain why some people with Alzheimer's disease (AD) don't respond after amyloid plaques are removed. 

Twelve minutes of cardio impacts 80% of circulating metabolites, improving cardiometabolic health. Brief bouts of exercise benefit insulin resistance, oxidative stress, inflammation, and longevity pathways.

In this study, middle-aged animals eating Mediterranean diets experienced better resilience to stress, lower cortisol, and slower nervous system aging than animals consuming a typical Western diet.

Researchers identify chronic inflammation, senescent cells, and activation of the protein CD38 as a driver of NAD+ decline, the crucial coenzyme needed for healthy metabolism, aging, and DNA repair.