In a study of over 52,000, those with brown fat were less likely to develop heart or metabolic-related conditions, including heart disease, heart failure, hypertension, and type 2 diabetes.

Cells that line blood vessels generate fat cells called fibro-inflammatory progenitors that promote inflammation, while the signaling molecule ZFP423 ameliorates this fat-related inflammation in mice. 

The MitoPunch transfers mitochondria and its DNA into over 100,000 mammalian cells simultaneously, allowing researchers to tailor specific genetic components and develop better disease treatments.

The conversion of beta-carotene (found in orange plants) into vitamin A protects against high cholesterol and requires the enzyme BCO1; up to 50% of the population have less active versions of BCO1.