Intestinal aging is aggravated by oxidative stress and mitochondrial dysfunction; the antioxidants resveratrol and pterostilbene may be important compounds for combatting these dysfunctions. 

Transplants of fecal matter housing gut microbes from young mice reversed age-related changes in the brain, suggesting that the microbiome may be a suitable target to promote healthy aging.

Gut microbes that break down the amino acid tryptophan secrete small molecules called indoles — and these indoles are a key factor in stimulating new neuron growth in the adult brain.

This study suggests that the newly discovered Dysosmobacter welbionis bacteria benefits body weight and metabolism, which could be a valuable intervention for targeting obesity and other metabolic disorders.