Understanding the changes to protein levels in plasma that precede the onset of dementia could yield insights into disease biology and highlight new biomarkers and avenues for intervention.

The central nervous system — the brain and spinal cord — is prone to decline as we age; the accumulation of immune CD8 T-Cells is a primary culprit that leads to neuronal damage.

From attenuating telomere loss to alleviating oxidative damage, ergothioneine’s potent antioxidant abilities have led researchers to coin the compound as the next “longevity vitamin.” 

The detrimental effects of skin aging after UV exposure can be reversed with NMN and probiotics, providing a starting point for this combination to prevent or treat sun-induced skin damage.