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Helping 200,000+ People Think Clearer and Achieve More 

Triple-Action Formula: Designed for Optimal Cellular Performance*  

Longevity B-Complex

60 Capsules, Methylated • SKU: PH717
Title

•  Boosts cellular energy production*1 
•  Helps maintain a positive mood*1-3   
•  Promotes a healthy stress response*1,2 

•  Maintains a well-functioning nervous system*2,4 
•  Supports methylation and homocysteine metabolism*1,2 
Title
$27.97
$39.95

Triple Lab Tested

Doctor Formulated 

Manufactured in the USA

100-Day Risk-Free Guarantee

Advanced B-Vitamin Technology for Peak Performance 

Longevity B-Complex delivers what your aging body actually needs—not just what’s trending. This doctor-developed formula provides a full-spectrum of essential B vitamins, delivered in a base of Himalayan shilajit for enhanced nutrient transport. Designed for morning use to help you feel sharper, more energized, and more resilient—everyday, at every stage of life.*1,2,4,5 

Advanced B-Vitamin Technology for Peak Performance 

Advancing Health & Longevity 
since 1988

For over 36 years, ProHealth has been dedicated to crafting the world’s highest-quality supplements—rooted in innovation, integrity, and a passion for healthy aging. With a long-standing A+ rating from the Better Business Bureau, our reputation for purity and potency has made us one of the most trusted names in the industry. Our commitment to scientific rigor, premium sourcing, and results you can feel continues to drive everything we do. 

Pioneering Longevity 

Since 1988 

For over 36 years, ProHealth has been dedicated to crafting the world’s highest-quality supplements—rooted in innovation, integrity, and a passion for healthy aging. With a long-standing A+ rating from the Better Business Bureau, our reputation for purity and potency has made us one of the most trusted names in the industry. Our commitment to scientific rigor, premium sourcing, and results you can feel continues to drive everything we do. 

Why Most B-Complex Supplements Fall Short 

Why Most B-Complex Supplements Fall Short 

The average B-complex is built for the masses, not for those optimizing longevity, performance, and cellular health. Most formulas still rely on outdated forms like folic acid and cyanocobalamin, paired with dosages that miss the mark—either too low to be effective or too high to be well-tolerated. 

 

This becomes especially problematic after age 50, when nutrient absorption declines, methylation slows, and your body’s demand for B vitamins increases. If your current supplement isn’t activated, methylated, or food-based, it’s likely falling short.1,6 

 

A truly effective B-complex should work with your biology—not against it—and deliver results you can actually feel.* 

The Science of Better B-Vitamins 

The Science of Better B-Vitamins 

B vitamins are critical coenzymes for virtually every major system in your body: from energy production and detoxification to neurotransmitter synthesis and DNA methylation.*1,2,7

But as you age, several challenges emerge. B vitamins are water-soluble and quickly excreted in urine, making it difficult to maintain adequate levels. Absorption also declines naturally with age, and more than 30% of adults over 60 are estimated to have suboptimal levels of vitamin B12. Up to 18% may also be low in thiamine—two of the most critical B vitamins for neurological and metabolic health.*1,6

This creates the perfect storm: your need for B vitamins increases, but your body’s ability to absorb and utilize them declines. Factors like reduced stomach acid, enzyme inefficiency, common medications, and slower methylation all contribute to this gap.*1,6 

 

Longevity B-Complex is designed to fill that gap—supporting foundational biological processes that tend to slow in your 50s and 60s, and delivering the preferred forms your body can recognize, absorb, and use right away.*1,4,6 

What Makes Longevity B-Complex Ideal for Aging Adults 

What Makes Longevity B-Complex Ideal for Aging Adults 

At ProHealth, we begin with 100% of the Daily Value of all essential B vitamins, sourced from fermented, food-based nutrients for enhanced absorption and digestive comfort. Then we go further—adding activated and methylated forms for therapeutic potency and optimal bioavailability.*4,8 

Methyl B12 (methylcobalamin) and methyl folate (5-MTHF) bypass common MTHFR gene variants that affect up to 40% of adults, ensuring immediate support for neurotransmitter synthesis, red blood cell formation, and homocysteine metabolism—without burdening the body’s detox pathways.*1,2,9

Active B6 (P5P, pyridoxal-5'-phosphate) combined with active B2 (R5P, riboflavin-5’-phosphate) provides direct support for the production of serotonin, dopamine, and GABA—critical for mood, stress resilience, and cognitive clarity as we age.*2,9

Benfotiamine, a fat-soluble form of B1, is included for its superior tissue uptake and potential benefits for nerve health and glucose metabolism—especially relevant in aging populations.*1,9,10 

Fermented forms of all B vitamins help drive the Krebs cycle and mitochondrial ATP production, the core energy-generating process that powers every cell in your body.*1,11,12

Shilajit (standardized for fulvic acid, source of trace minerals) acts as a powerful nutrient driver, helping transport B vitamins into the mitochondria where they’re converted into usable energy. This is especially important in older adults, where nutrient transport and mitochondrial efficiency naturally decline.*5,13 

How We Compare: 
Longevity B-Complex vs. Others 

How We Compare: 
Longevity B-Complex vs. Others 

Feature

Longevity B-Complex

Other

Methyl B12  

Methyl folate 

Activated forms 

Varies

Benfotiamine 

Fermented vitamins 

Shilajit extract 

Mitochondrial focus 

Limited

Designed specifically for 50+ 

100-day guarantee 

What you may notice overtime

What You May Notice Over Time 

Weeks 1-2

Increased daily energy, brighter mood, greater motivation*

Weeks 3-4

More sustained energy, sharper mental clarity, better stress response*

Weeks 6-8

Deeper resilience, enhanced recovery, reduced feeling of fatigue*

Long-term

Optimized homocysteine, enhanced methylation activity, improved quality of life* 

Why Thousands Trust ProHealth

What Makes Ours Better?

Doctor Formulated

Expertly developed with a deep understanding of B-vitamin metabolism, this formula targets the key absorption and utilization barriers that emerge with age—using methylated, activated, and fermented forms for maximum effectiveness.* 

Longevity Focused

We leverage cutting-edge advancements in aging research to formulate products that address the fundamental causes of aging.*

Triple Lab Tested

Every product is tested three times by independent 3rd-party labs to ensure we meet the highest standards.

USA Manufacturing Excellence

Made in FDA-regulated, GMP-certified facilities in the USA for the highest quality and safety standards.

A Word from our Chief Science Officer 

A Word from our Chief Science Officer 

“B vitamins are often overlooked—but they’re some of the most powerful molecules for longevity. In their activated, methylated, and fermented forms, they don’t just support energy—they unlock it at the cellular level, fueling mitochondria, optimizing methylation, and driving detox pathways. I designed our Longevity B-Complex to go beyond standard B formulas, combining next-generation forms with shilajit and benfotiamine to help nourish the body’s core energy systems and spark vitality from within.” 

Confidence In Every Bottle

Confidence In Every Bottle

100-Day Risk-Free Guarantee

We stand behind our products. If you're not satisfied please reach out to our Santa Barbara, CA office for a full refund within 100 days – no hassle, no questions.

Complete Transparency

In a market crowded with questionable supplements, we set ourselves apart by publishing third-party lab test results. We're commited to full transparency—so you know exactly what's in every bottle.

Free Shipping

Whether you're a first-time or returning customer, we offer free U.S. shipping on orders over $30—making your shopping experience even easier and more convenient.

Meet Our Ingredients

Meet Our Ingredients
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B1 (Benfotiamine)

Fat-soluble form with superior bioavailability for glucose metabolism and nerve protection.*1,9,10

B2 (Riboflavin-5'-Phosphate)

Active coenzyme form supporting cellular energy production and antioxidant defenses.*1,14 
Product not found
Product not found

B7 (Biotin)

Natural form supporting fatty acid metabolism and healthy hair, skin, and nails.*1,9

B9 (5-MTHF)

Methylated folate bypassing MTHFR mutations, essential for DNA synthesis and cardiovascular health.*1,2,9
Product not found

B6 (P5P)

Active form requiring no conversion, critical for neurotransmitter synthesis and methylation.*2,9

*These statements have not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.

A Smarter B-Complex, Backed by Science

Unlike generic formulas, Longevity B-Complex is expertly crafted to work with your body—supporting energy, mood, brain health, and stress resilience at the cellular level.* 

 

With bioavailable, fermented nutrients and mitochondrial activators like shilajit, this formula helps close the absorption gap that comes with age. With bioavailable, fermented nutrients and mitochondrial activators like shilajit, this formula helps close the absorption gap that comes with age. Trust the only B-complex designed to help you feel sharper, stronger, and more vibrant—every day.*

Customer Reviews

Based on 10 reviews
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M
MURAT A.

Murat

C
Constance M.
B Complex should be in most people's diets

This looks like a good B Complex supplement from a good company.

1
1ucy
Everything I need in a B-complex

I'm so pleased with all the ingredients in this product. I feel amazing and love that this contains fermented vitamins and benfotamine. I have incredible energy and my labs look great.

S
Sally M.

Best product

V
Valerie M.
Positive response

like the B12 extreme that I took previously the longevity B complex helps me have more energy and clear thinking that I really need.

A
Anne F.
First time user

This is my first time using this product and as with any product of this nature, that aids in healthy aging, it’s a little too soon to speak to it with benefits, but I will be ordering again.

L
Lynnan S.
Feel Great

More energy and feeling great after using this product.

D
Douglas k.

Very nice results

T
Trevor B.
Clean and potent

No nervous energy nor stomach discomfort. Best b vitamin I’ve ever tried

J
Jeremy C.
Triple-action formula

I will never overlook b vitamins again. Prohealth's triple lab 3rd party testing and published COA's gives me confidence in every bottle.

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References

References

1Kennedy DO. Nutrients. 2016;8(2):68. 

2Young LM et al. Nutrients. 2019;11(9):2232. 

3Moore K et al. J Am Med Dir Assoc. 2019;20(5):551-557. 

4Haas E. Staying Healthy with Nutrition. 2006. 

5Kamgar E et al. Crit Rev Anal Chem. 2025;55(3):461-473. 

6Harris JR et al. Biochemistry and Cell Biology of Ageing. 2018(90):1-531. 

7Schellack G et al. S Afr Pharm J. 2015;82(4):28-33. 

8Lindschinger M et al. Oxid Med Cell Longev. 2019;2019:1-14. 

9McCabe D et al. JBI Database System Rev Implement Rep. 2017;15(2):402-453. 

10Hrubša M et al. Nutrients. 2022;14(3):484. 

11Hanna M et al. Perm J. 2022;26(2):89-97. 

12Huskisson E et al. J Int Med Res. 2007;35(3):277-289. 

13Stohs SJ. Phytother Res. 2014;28(4):475-479. 

14Ali MA et al. Nutrients. 2022;14(19):3940.