People with Major Depressive Disorder (MDD) have increased rates of DNA methylation, which is a proxy for biological aging, averaging two years older in internal age in this study.

Male baboons who climbed the social ladder faster and competed the most to achieve dominance in the group had faster rates of biological aging, as measured by DNA methylation.

Deleting the protein tau led to improved cognitive abilities and mitochondrial function in normally aged mice; Tau protein buildup plays a vital role in the development of Alzheimer's disease.

A novel biomarker tracks the efficacy of senolytics — drugs that eliminate senescent cells that have permanently stopped dividing but remain dysfunctional in the body and promote inflammation.