Researchers have uncovered a new function of the gene BMI1, which prevents neurons' DNA from disorganizing into structures called G4, seen in Alzheimer's diseased brains.

Gene regulation therapy using "zinc finger proteins" was used to treat Alzheimers disease in mice by binding to the DNA that codes for the harmful protein Tau that accumulates in Alzheimer's brains.

The blood-brain barrier (the border protecting the brain from toxins) leaks as we age, and we lose cells called pericytes. Pericyte health can be preserved by regular exercise and caloric restriction.

Altered liver metabolism of the amino acid alanine is implicated in type 2 diabetes; silencing the enzymes that break down alanine in liver cells effectively reverses high blood sugar and muscle loss.