Longevity Articles

How to Find the Best NMN Supplements

The best NMN supplements will have 99% purity or higher.

Nicotinamide mononucleotide (NMN) is showing promising health and longevity benefits due to its unique ability to convert into oxidized nicotinamide adenine dinucleotide (NAD+), a coenzyme found in all cells that assists with energizing everyday bodily functions such as energy production, metabolism, and gene expression. As we age, NAD+ levels naturally decline and our cells stop dividing, which contributes to the loss of function seen in people who are aged and those who suffer from chronic disease. This process is called cell senescence. By increasing levels of NAD+ in our system by taking NMN supplements, we can offset senescence and improve our cellular health.

The most well-known NMN benefits include: 

Just as people’s immunity is impacted by different variables like genetics, environmental influences, diet, and lifestyle, NMN supplements are also composed differently. You should know what to look for in NMN supplements and be aware of which products blend best with your body and personally provide the most value. Let’s take a look at how you can determine what the best NMN supplement is for you.

How to Choose the Best NMN Supplement for You: What to Look For

1. A Supplier with an Excellent Reputation

Quality NMN comes from quality suppliers. But how can you tell a company is reputable? You can check the Better Business Bureau to see how long the company has been in business, what their current rating is, and if there have been any complaints filed against them. An esteemed company will have good reviews and ratings across multiple platforms and is a great place to start when deciding on the right product so you can get the benefits of NMN. Check the company website or do an internet search to see if they have accumulated positive NMN supplement reviews.

2. Good Manufacturing Facility Practices

A respected NMN supplier will have ethical operating procedures when it comes to manufacturing. A facility producing NMN should be FDA-registered and FDA-compliant in current Good Manufacturing Practice (GMP) regulations. Being GMP-certified means the FDA has found the company’s facilities, equipment, and ability to manufacture NMN products up to par with the standard regulations. You may also consider looking into whether the facility is climate-controlled. NMN supplements can quickly degrade at high temperatures, which is why they should be produced in a facility where appropriate temperatures are kept during the manufacturing process.

3. Third-Party Testing

One of the most important things to check when determining which NMN supplement is the best is whether or not the manufacturing company submits its product for independent, third-party testing. Testing by a non-biased party will ensure the product is pure (99% or higher) pharmaceutical-grade NMN, free of heavy metals. You can check the supplier’s website for third-party testing information, or contact their customer service directly. Verification of third-party testing is a simple way to ensure you’re buying from a reputable source. Any company using third-party testing should be happy to share that information with you.

4. Product Purity

As previously mentioned, the best NMN supplements will have 99% purity or higher. It will also not contain any fillers or byproducts such as GMOs, dairy, egg, soy, gluten, artificial chemicals, heavy metals, or solvents used in the actual processing of the product. Check labels for any of these ingredients, or you can always directly contact the company to ask about their NMN production process.

5. Pricing

It’s always tempting to try to save money every chance you can get, but with NMN specifically, you get what you pay for. Low-cost NMN will likely be food-grade, not pharmaceutical grade, which means the NMN benefits aren’t the same. It comes back to the involved process required to create a product with 99% purity or higher. If the price is low, the percentage of NMN is likely also low — if it exists at all. Considering your budget is important when determining where to buy NMN supplements, but you may end up paying more in the long run when opting for lower-priced NMN products if you don’t see any health benefits from them.

6. Consumer-Satisfaction Guarantee

Highly regarded NMN supplement companies usually provide some kind of guarantee of compensation should you find yourself not fully satisfied with the results of your purchase. Check the fine print on a supplier’s website or call the company to verify whether they afford any money-back guarantees if returned by a specific date. For example, some companies may offer a 30-day money-back guarantee, which should be enough time to determine if the NMN supplement product is a good fit for you.

7. Product Research

With NMN being more heavily researched for its benefits to overall health and longevity as a necessary NAD+ precursor, the chances of a particular NMN product being used in human clinical trials exist. Only NMN products whose quality and purity can be verified are used for studies, so you may want to see if the product you’re interested in is being considered or used for research purposes. While most companies proudly display this online, you can always call customer service to double-check if you can’t locate that information yourself.

8. Form of Delivery

Supplementary NMN can be purchased as powder, lozenges, tablets, and capsules, each having a unique ability to get into your system in different ways. When figuring out how to choose NMN supplements, your personal preference is really the key. If tablets and capsules are difficult to swallow, starting with NMN powder or a lozenge may be the best option for you. For convenience purposes while traveling, for example, an easy-to-carry pill or lozenge may provide the best solution. A good company will likely have a variety of NMN forms available to suit your needs, so consider which form may be best for you. No matter which form you take, NMN is absorbed from the gut and into the blood within two to three minutes, and completely absorbed into tissue within 15 minutes, according to a study in Biomolecules. Once in the liver, it is then converted and stored as NAD+ and persists for 30 minutes.

Key Takeaways

Finding the best NMN supplement to assist in your efforts to recapture and maintain your youth can be easy when you know what questions to ask and what answers to listen for. A supplier with a long-standing, good reputation that adheres to FDA regulations will most likely provide you with a high-quality, third-party tested, pharmaceutical-grade NMN product. Don’t forget to read NMN supplement reviews, and when in doubt, go directly to customer service with any concerns or questions you may have. When you get close to committing to a purchase, remember to check for any satisfaction guarantees to confirm you are making a risk-free, sound investment in your health.


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Center for Drug Evaluation and Research. (n.d.). Current Good Manufacturing Practice (CGMP) Regulations. Retrieved June 15, 2020, from https://www.fda.gov/drugs/pharmaceutical-quality-resources/current-good-manufacturing-practice-cgmp-regulations

Office of Regulatory Affairs. (n.d.). Registration and Listing. Retrieved June 15, 2020, from https://www.fda.gov/industry/fda-basics-industry/registration-and-listing

Poddar SK, Sifat AE, Haque S, Nahid NA, Chowdhury S, Mehedi I. Nicotinamide Mononucleotide: Exploration of Diverse Therapeutic Applications of a Potential Molecule. Biomolecules. 2019;9(1):34. Published 2019 Jan 21. doi:10.3390/biom9010034

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