Longevity B-Complex - 60 capsules

Triple-Action Formula: Designed for Optimal Cellular Performance*

• Boosts cellular energy production*¹
• Helps maintain a positive mood*^1-3
• Promotes a healthy stress response*^1,2
• Maintains a well-functioning nervous system*^2,4
• Supports methylation and homocysteine metabolism*^1,2

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Advanced B-Vitamin Technology for Peak Performance

Longevity B-Complex delivers what your aging body actually needs—not just what’s trending. This doctor-developed formula provides a full-spectrum of essential B vitamins, delivered in a base of Himalayan shilajit for enhanced nutrient transport. Designed for morning use to help you feel sharper, more energized, and more resilient—everyday, at every stage of life.* ^1,2,4,5

Pioneering Longevity Since 1988

For over 36 years, ProHealth has been dedicated to crafting the world’s highest-quality supplements—rooted in innovation, integrity, and a passion for healthy aging. With a long-standing A+ rating from the Better Business Bureau, our reputation for purity and potency has made us one of the most trusted names in the industry. Our commitment to scientific rigor, premium sourcing, and results you can feel continues to drive everything we do.

Why Most B-Complex Supplements Fall Short

The average B-complex is built for the masses, not for those optimizing longevity, performance, and cellular health. Most formulas still rely on outdated forms like folic acid and cyanocobalamin, paired with dosages that miss the mark—either too low to be effective or too high to be well-tolerated.

This becomes especially problematic after age 50, when nutrient absorption declines, methylation slows, and your body’s demand for B vitamins increases. If your current supplement isn’t activated, methylated, or food-based, it’s likely falling short.^1,6

A truly effective B-complex should work with your biology—not against it—and deliver results you can actually feel.*

The Science of Better B-Vitamins

B vitamins are critical coenzymes for virtually every major system in your body: from energy production and detoxification to neurotransmitter synthesis and DNA methylation.*^1,2,7

But as you age, several challenges emerge. B vitamins are water-soluble and quickly excreted in urine, making it difficult to maintain adequate levels. Absorption also declines naturally with age, and more than 30% of adults over 60 are estimated to have suboptimal levels of vitamin B12. Up to 18% may also be low in thiamine—two of the most critical B vitamins for neurological and metabolic health.*^1,6

This creates the perfect storm: your need for B vitamins increases, but your body’s ability to absorb and utilize them declines. Factors like reduced stomach acid, enzyme inefficiency, common medications, and slower methylation all contribute to this gap.*^1,6

Longevity B-Complex is designed to fill that gap—supporting foundational biological processes that tend to slow in your 50s and 60s, and delivering the preferred forms your body can recognize, absorb, and use right away.*^1,4,6

What Makes Longevity B-Complex Ideal for Aging Adults

At ProHealth, we begin with 100% of the Daily Value of all essential B vitamins, sourced from fermented, food-based nutrients for enhanced absorption and digestive comfort. Then we go further—adding activated and methylated forms for therapeutic potency and optimal bioavailability.*^4,8

• Methyl B12 (methylcobalamin) and methyl folate (5-MTHF) bypass common MTHFR gene variants that affect up to 40% of adults, ensuring immediate support for neurotransmitter synthesis, red blood cell formation, and homocysteine metabolism—without burdening the body’s detox pathways.*^1,2,9
• Active B6 (P5P, pyridoxal-5'-phosphate) combined with active B2 (R5P, riboflavin-5’-phosphate) provides direct support for the production of serotonin, dopamine, and GABA—critical for mood, stress resilience, and cognitive clarity as we age.*^2,9
• Benfotiamine, a fat-soluble form of B1, is included for its superior tissue uptake and potential benefits for nerve health and glucose metabolism—especially relevant in aging populations.*^1,9,10
• Fermented forms of all B vitamins help drive the Krebs cycle and mitochondrial ATP production, the core energy-generating process that powers every cell in your body.*^1,11,12
• Shilajit (standardized for fulvic acid, source of trace minerals) acts as a powerful nutrient driver, helping transport B vitamins into the mitochondria where they’re converted into usable energy. This is especially important in older adults, where nutrient transport and mitochondrial efficiency naturally decline.*^5,13

How We Compare: Longevity B-Complex vs. Others

What You May Notice Over Time

Weeks 1–2: Increased daily energy, brighter mood, greater motivation*
Weeks 3–4: More sustained energy, sharper mental clarity, better stress response*
Weeks 6–8: Deeper resilience, enhanced recovery, reduced feeling of fatigue*
Long-term: Optimized homocysteine, enhanced methylation activity, improved quality of life*

Confidence in Every Bottle

• Doctor-Formulated: Expertly developed with a deep understanding of B-vitamin metabolism, this formula targets the key absorption and utilization barriers that emerge with age—using methylated, activated, and fermented forms for maximum effectiveness.*
• Longevity Focused: We leverage cutting-edge advancements in aging research to formulate products that address the fundamental causes of aging.*
• Triple Lab Tested: Every product is tested three times by independent 3rd-party labs to ensure we meet the highest standards.
•  Complete Transparency: In an industry flooded with fake supplements, we stand apart by publishing our 3rd-party lab test results. We’re committed to showing you exactly what’s in every bottle, so you can feel confident in what you’re putting into your body. 
• USA Manufacturing Excellence: Made in FDA-regulated, GMP-certified facilities in the USA for the highest quality and safety standards. 
• 100-Day Risk-Free Guarantee: We stand behind our products. Not satisfied? Reach out to our Santa Barbara, CA office for a full refund within 100 days.

A Word from our Chief Science Officer

“B vitamins are often overlooked—but they’re some of the most powerful molecules for longevity. In their activated, methylated, and fermented forms, they don’t just support energy—they unlock it at the cellular level, fueling mitochondria, optimizing methylation, and driving detox pathways. I designed our Longevity B-Complex to go beyond standard B formulas, combining next-generation forms with shilajit and benfotiamine to help nourish the body’s core energy systems and spark vitality from within.”

100-Day Risk-Free Guarantee

We’re so confident in Longevity B-Complex, we offer a full 100-day return policy. If you don’t feel a measurable difference, simply return the bottle—no questions asked.

Invest in the Long Game

Order now and join the 200,000+ people who trust ProHealth for their longevity care.

Ingredient Info

• B1 (Benfotiamine): Fat-soluble form with superior bioavailability for glucose metabolism and nerve protection.*^1,9,10
• B2 (Riboflavin-5'-Phosphate): Active coenzyme form supporting cellular energy production and antioxidant defenses.*^1,14
• B3 (Niacinamide): Non-flushing NAD+ precursor essential for cellular energy and DNA repair.*^1,10
• B5 (Pantothenic Acid): Essential for Coenzyme A synthesis, supporting adrenal function and energy metabolism.*^1,7
• B6 (P5P): Active form requiring no conversion, critical for neurotransmitter synthesis and methylation.*^2,9
• B7 (Biotin): Natural form supporting fatty acid metabolism and healthy hair, skin, and nails.*^1,9
• B9 (5-MTHF): Methylated folate bypassing MTHFR mutations, essential for DNA synthesis and cardiovascular health.*^1,2,9
• B12 (Methylcobalamin): Neurologically active form, essential for optimal nerve and brain function.*^1,2,9
• Shilajit Extract: Mineral-rich resin enhancing nutrient transport and mitochondrial energy production.*⁵

References:

1. Kennedy DO. Nutrients. 2016;8(2):68.
2. Young LM et al. Nutrients. 2019;11(9):2232.
3. Moore K et al. J Am Med Dir Assoc. 2019;20(5):551-557.
4. Haas E. Staying Healthy with Nutrition. 2006.
5. Kamgar E et al. Crit Rev Anal Chem. 2025;55(3):461-473.
6. Harris JR et al. Biochemistry and Cell Biology of Ageing. 2018(90):1-531.
7. Schellack G et al. S Afr Pharm J. 2015;82(4):28-33.
8. Lindschinger M et al. Oxid Med Cell Longev. 2019;2019:1-14.
9. McCabe D et al. JBI Database System Rev Implement Rep. 2017;15(2):402-453.
10. Hrubša M et al. Nutrients. 2022;14(3):484.
11. Hanna M et al. Perm J. 2022;26(2):89-97.
12. Huskisson E et al. J Int Med Res. 2007;35(3):277-289.
13. Stohs SJ. Phytother Res. 2014;28(4):475-479.
14. Ali MA et al. Nutrients. 2022;14(19):3940.