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Bone Health
DNA HealthFree Nutritional Advisor
Free Nutritional AdvisorSupport Energy Production, Bone Strength, and Metabolic Function With Age
- Supports healthy aging processes
- Supports heart, bone, and metabolic health
- Supports cognitive vitality
- Helps to boost antioxidant levels inside cells
Research-Supported Benefits:
Promotes Metabolic Function and Longevity: Alpha-ketoglutarate (AKG) is a compound that is created naturally in the body but tends to diminish with age. In supplement form, AKG can be attached to a calcium salt (Ca-AKG), which has been studied for its role in supporting metabolic function and longevity. (1)
Stimulates Autophagy: Autophagy, our internal recycling process that removes dysfunctional cells, decreases with age. Ca-AKG has been found to support this process. (2)
Aides in Bone and Muscle Health: Ca-AKG is involved in stimulating protein synthesis and energy production in the body, as it is a vital component of the Krebs cycle - the process that creates ATP (energy) from food. Ca-AKG is also a source of the essential amino acids needed to make collagen, which is a protein that helps to support bone and muscle health. (3)
Supports Blood Sugar Regulation: As we age, our bodies become less efficient at regulating blood sugar. Research shows that Ca-AKG can help to support healthy blood sugar levels. (3)
Supports Cellular Health: The mitochondria, our cells’ main energy hub decreases with age leading to aging and numerous age-related health concerns. Ca-AKG has been found to activate AMPK a pathway that helps maintain cellular energy and support cellular function. (3)
Improves Antioxidant Levels: Ca-AKG has also been shown to boost cellular antioxidant levels in aged mice, which helped support the mice’s blood vessel elasticity - a measure of good cardiovascular health. (4)
References:
1. Asadi Shahmirzadi A, Edgar D, Liao CY, et al. Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice. Cell Metab. 2020;32(3):447-456.e6. doi:10.1016/j.cmet.2020.08.004
2. Chin R, Fu X, Pai M., et al. The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Nature. 2014;510:397–40. https://doi.org/10.1038/nature13264
3. Wu N, Yang M, Gaur U, Xu H, Yao Y, Li D. Alpha-Ketoglutarate: Physiological Functions and Applications. Biomol Ther (Seoul). 2016;24(1):1-8. doi:10.4062/biomolther.2015.078
4. Niemiec T, Sikorska J, Harrison A, et al. Alpha-ketoglutarate stabilizes redox homeostasis and improves arterial elasticity in aged mice. J Physiol Pharmacol. 2011;62(1):37-43.
5. Demidenko O, Barardo D, Budovskii V, et al. Rejuvant®, a potential life-extending compound formulation with alpha-ketoglutarate and vitamins, conferred an average 8 year reduction in biological aging, after an average of 7 months of use, in the TruAge DNA methylation test. Aging (Albany NY). 2021;13(22):24485-24499. doi:10.18632/aging.203736
6. Wu N, Yang M, Gaur U, Xu H, Yao Y, Li D. Alpha-Ketoglutarate: Physiological Functions and Applications. Biomol Ther (Seoul). 2016;24(1):1-8. doi:10.4062/biomolther.2015.078
7. Wang Y, Deng P, Liu Y, et al. Alpha-ketoglutarate ameliorates age-related osteoporosis via regulating histone methylations. Nat Commun. 2020;11(1):5596. Published 2020 Nov 5. doi:10.1038/s41467-020-19360-
8. Niemiec T, Sikorska J, Harrison A, et al. Alpha-ketoglutarate stabilizes redox homeostasis and improves arterial elasticity in aged mice. J Physiol Pharmacol. 2011;62(1):37-43.
9. Wu N, Yang M, Gaur U, Xu H, Yao Y, Li D. Alpha-Ketoglutarate: Physiological Functions and Applications. Biomol Ther (Seoul). 2016;24(1):1-8. doi:10.4062/biomolther.2015.078
10. Asadi Shahmirzadi A, Edgar D, Liao CY, et al. Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice. Cell Metab. 2020;32(3):447-456.e6. doi:10.1016/j.cmet.2020.08.004
11. Chin R, Fu X, Pai M., et al. The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Nature. 2014;510:397–40. https://doi.org/10.1038/nature13264
| Supplement Facts | ||
|---|---|---|
| Serving Size: 2 Capsules | ||
| Servings Per Container: 30 | ||
| Amount Per Serving | %DV | |
| Calcium (as Alpha Ketoglutarate) |
180 mg | 14% |
| Calcium Alpha Ketoglutarate) | 1000 mg | † |
| † Daily Value (DV) not established. | ||
- OTHER INGREDIENTS: Hypromellose (capsule), rice flour.
-
SUGGESTED DAILY USE: Take two (2) capsules in the morning, with or without food, for daily energy
support. Or take four (4) capsules 30-60 minutes before exercise for athletic support.* - CAUTION: Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place.
- Alpha-ketoglutarate (AKG) is a compound that is created naturally in the body but tends to diminish with age. In supplement form, AKG can be attached to a calcium salt (Ca-AKG), which has been studied for its role in supporting metabolic function and longevity. 6
- Ca-AKG is involved in stimulating protein synthesis and energy production in the body, as it is a vital component of the Krebs cycle - the process that creates ATP (energy) from food. Ca-AKG is also a source of the essential amino acids needed to make collagen, which is a protein that helps to support bone and muscle health.
- Ca-AKG facilitates our internal recycling process known as autophagy, which removes dysfunctional cells, cell parts and proteins from the body. Autophagy tends to decrease with age, so Ca-AKG may be able to help support this process.
- Adding calcium to AKG helps to slow the absorption of AKG allowing it to work longer in the body.
- Better Absorption. Compared to other products that commonly use unbound AKG or AKG bound to arginine, our AKG is bound to calcium. This combination has been shown to promote extended lifespan and health span in mice, even when administered late in life. It also helps to slow the absorption allowing it to work longer in the body.
- Research-Supported. Calcium AKG Longevity is formulated using 1,000 mg of calcium alpha ketoglutarate, which has been shown in clinical research to promote longevity by reversing biological age (measured by biological age tests), improve markers of heart health and decrease risk of age-related decline in bone health.
- Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.
- Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.
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Trusted Brand for Calcium AKG
"This is an awesome product. It has slowed and reversed my graying hair. I am 52 and would usually color my edges every 3 weeks but since using this product (1x every other day) for the last month, I've noticed way less gray coming in and have decided to stop dying my edges. Good quality product!"
I am very satisfied with Calcium AKG Longevity. It’s a high-quality supplement that fits perfectly into the growing market of health and longevity products. I feel more energetic and notice better recovery after exercise. This is a strong product that I believe will become even more popular as more people focus on healthy aging. Highly recommended!
A 1000 mg dose of Calcium Alpha-Ketogautaric (AKG) becomes the fuel for the mitochondria.
It is said to be the basis for human longevity by helping to form collagen, helping self-predation, and activating metabolism.
When I ingest it, I feel energized, not tired, and vitality in my life.
After about 7 months, take a leave of absence.
I'm going to take it again.
I think it is an essential health supplement for young maintenance.
Calcium AKG Longevity - 1,000 mg per serving, 60 capsules
Great supplement to help yourself maintain your cellular health… good capsules size, easy to swallow, easy to order.
Calcium AKG Longevity - 1,000 mg per serving, 60 capsules - 3 pack
Calcium AKG Longevity - 1,000 mg per serving, 60 capsules - 3 pack
Calcium AKG Longevity - 1,000 mg per serving, 60 capsules
I’ve been taking it for around two weeks. I feel pretty good overall, and it’s also helped with my energy levels. I don’t get tired as easily anymore, so I’ll keep using it.
Definitely notice the methylation and autophagy benefits in the form of more engery.
Bones are getting better
Best Calcium AKG in the market
to see big results but I do think it is somewhat helpful at least. I think prohealth is a good brand.
In theory should work.
No discomfort
Calcium AKG Longevity - 1,000 mg per serving, 60 capsules - 3 pack
So, I did some research and found that taking this supplement could help. I’ve been taking it for a month now, and I feel re-energized—I have the urge to get things done just like I did 20 years ago. Now, I plan to take it regularly. As we get older, our bodies lose their natural vitality, so we need to replenish it
Great add to any mitochondrial/longevity stack. Works great synergistically with NAD precursors. Noticeable boost in energy level.
Seems to be going well so far. Seems good quality.
I have recently realized how important a calcium supplement is, and for me the ProHealth offering is the best and most cost effective. I have noticed an increased feeling of strength and skin elasticity since starting the supplement. I hope this continues.
I have been using this for about a month. I take it as soon as I wake up and am definitely feeling a good boost. I was glad to find that this is acceptable to take with coffee. Hoping to gain more athletic stamina with continued use. I think I’m getting there!
Calcium AKG Longevity - 1,000 mg per serving, 60 capsules
Always trust Prohealth's products, keep adding more of their product on my supplement list
Calcium AKG Longevity - 1,000 mg per serving, 60 capsules
I'm just trying the Calcium AKG capsules for the first time, but so far I'm feeling pretty good. I'll keep going with these for the rest of my first 90 days and decide if I want to keep going.
Finding a calcium product that addresses my needs has been filled with Calcium AKG, I trust Prohealth to supply supplements that are tested and meet my require=rements.
I’ve been taking Calcium AKG Longevity – 1,000 mg per serving, 60 capsules for a few months now, and I couldn’t be happier with the results. This supplement has been a reliable addition to my daily routine, and I genuinely feel the difference in my overall sense of well-being.
What I love most is how easy it is to take—just one serving a day fits seamlessly into my schedule. Since I started using it, I’ve noticed better support for my day-to-day energy and overall nutritional balance. Calcium AKG has helped me feel confident that I’m making thoughtful choices about my health, and it complements my diet and lifestyle without any fuss.
If you’re looking for a high-quality calcium supplement that goes beyond the basics and supports your long-term wellness goals, this one is definitely worth considering. I highly recommend it to anyone trying to make a smarter health decision—you’ll appreciate the consistency and peace of mind it brings!
Calcium AKG Longevity - 1,000 mg per serving, 60 capsules - 3 pack
Just started taking it. Don't notice anything yet
Is as described. Would recommend.