Researchers found that highly irregular bedtimes in midlife were linked to roughly double the risk of serious heart problems, highlighting sleep timing as a key longevity lever.

A new review suggests your heart may benefit most from a mix of cardio and strength work, with flexible timing—from daily sessions to “weekend warrior” workouts.  

The natural hormone FGF21 can activate a hindbrain circuit in mice that boosts energy burning and weight loss without suppressing appetite, pointing to new brain-based strategies for metabolic health.  

Researchers found that clearing senescent “zombie” immune cells reversed fatty liver damage in mice, hinting that targeting cellular senescence may help combat age‑related disease.