S-Acetyl Glutathione - 300 mg, 60 capsules

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Supports detoxification, brain health and cellular functions.

  • Supports healthy cell function and healthy aging
  • Supports liver detoxification
  • Supports the brain and nervous system

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Research-Supported Benefits:

Supports Cellular Health. Glutathione is our body’s most abundant antioxidant, playing a critical role in protecting the body from oxidative stress. Glutathione helps to regulate several cellular events, such as gene expression, protein and DNA synthesis, immune response and cell growth. In addition to being an antioxidant itself, glutathione is also a cofactor for several other antioxidant enzymes1-3

Supports Detoxification. Glutathione supports both phase 1 and phase 2 detoxification in the liver, helping to neutralize and excrete harmful toxins. Glutathione not only binds to toxins before they can bind to and damage cells, but it also transforms toxins into a water-soluble form for further filtering and easy excretion through the urinary system. Dysfunctional detoxification pathways can lead to liver damage, DNA damage and increased cellular stress.4

Supports Healthy Aging. Glutathione deficiency contributes to oxidative stress, which can accelerate aging and the development of age-related disorders. Our mitochondria‚ÄĒthe cells‚Äô energy production centers‚ÄĒare dependent on glutathione, which can cross mitochondrial membranes and minimize reactive oxygen species (ROS) buildup. Healthy mitochondrial function is vital for healthy aging.5

Supports Brain and Nervous System Health. Glutathione is necessary for neutralizing ROS in the brain, which can lead to poor cognitive function. Research shows that reduced glutathione levels in the brain are linked to the development of neurological conditions.6, 7


1. Wu G, Fang YZ, Yang S, Lupton JR, Turner ND. Glutathione metabolism and its implications for health. J Nutr. 2004;134(3):489-492. doi:10.1093/jn/134.3.489 

2. Chatterjee A. Reduced glutathione: a radioprotector or a modulator of DNA-repair activity?. Nutrients. 2013;5(2):525-542. Published 2013 Feb 7. doi:10.3390/nu5020525 doi:10.3390/nu5020525 

3. Forman HJ, Zhang H, Rinna A. Glutathione: overview of its protective roles, measurement, and biosynthesis. Mol Aspects Med. 2009;30(1-2):1-12. doi:10.1016/j.mam.2008.08.006 

4. Pizzorno J. Glutathione!. Integr Med (Encinitas). 2014;13(1):8-12. PMID: 26770075 

5. Marí M, Morales A, Colell A, García-Ruiz C, Fernández-Checa JC. Mitochondrial glutathione, a key survival antioxidant. Antioxid Redox Signal. 2009;11(11):2685-2700. doi:10.1089/ARS.2009.2695 

6. Dringen R. Metabolism and functions of glutathione in brain. Prog Neurobiol. 2000;62(6):649-671. doi:10.1016/s0301-0082(99)00060-x 

7. Mandal PK, Saharan S, Tripathi M, Murari G. Brain glutathione levels--a novel biomarker for mild cognitive impairment. Biol Psychiatry. 2015;78(10):702-710. doi:10.1016/j.biopsych.2015.04.005 

8. Ballatori N, Krance SM, Notenboom S, Shi S, Tieu K, Hammond CL. Glutathione dysregulation and the etiology and progression of human diseases. Biol Chem. 2009;390(3):191-214. doi:10.1515/BC.2009.033 

9. Di Paola R, Modafferi S, Siracusa R, et al. S-Acetyl-Glutathione Attenuates Carbon Tetrachloride-Induced Liver Injury by Modulating Oxidative Imbalance and Inflammation. Int J Mol Sci. 2022;23(8):4429. Published 2022 Apr 17.

  • Glutathione functions extensively in tissues and organs throughout the body.¬†
  • It plays critical roles in protecting the body from oxidative stress, maintaining cellular functions, and supporting healthy immune function.¬†
  • Many factors can increase cellular exposure to oxidative insult, and therefore increase cellular consumption of nutrients‚ÄĒsuch as glutathione‚ÄĒthat provide antioxidant activity.¬†
  • This may result in a fierce cycle of oxidative stress and challenges to detoxification. Complete biotransformation and protection from oxidative stress are important to maintaining cellular integrity and tissue health. (8)¬†
  • Much information related to mitochondrial health has surfaced in scientific literature. Mitochondria, the energy-producing powerhouses of cells, are also the primary intracellular site of oxygen consumption and the major source of reactive oxygen species (ROS).¬†
  • S-acetyl glutathione has been shown to cross the membrane of the mitochondria, increasing the organelle's activity and minimizing ROS.(5)
  • Reduction of ROS is associated with maintaining mitochondrial integrity and function, and improved mitochondrial health is believed to support overall health and energy.¬†¬†
  • Use of stomach acid-resistant capsules (DRcaps) further protect stability. Laboratory data showed that S-acetyl glutathione increased intracellular glutathione and had a positive effect on many oxidative stress biomarkers. (9)
Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving %DV
S-Acetyl-L-Glutathione (Emothion¬ģ) 300 mg ‚Ć
† Daily Value not established

Emothion¬ģ is a registered trademark of Gnosis SpA. US Patent No. 6,902,912 European Patent No. 1391517 JP Patent No. 4342860

  • OTHER INGREDIENTS: Delayed release vegetable capsule, microcrystalline cellulose, magnesium stearate.
  • DOES NOT CONTAIN: Dairy, egg, soy, wheat, gluten, corn, fish, shellfish, tree nuts, peanuts.
  • SUGGESTED DAILY USE: Take 1 capsule daily without food, or as directed by your healthcare professional.
  • CAUTION: Not intended for use if you are pregnant or nursing. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.
  • NOTE: Do not eat freshness packet. Keep in bottle. Store in a cool, dry place, away from direct sunlight. Do not use if tamper-evident packaging is broken. KEEP OUT OF REACH OF CHILDREN

Increased Bioavailability. Traditional glutathione supplements have poor absorption in the body. The S-acetyl glutathione in Emothion¬ģ is in crystalline form, which has a quicker dissolution rate and more efficient absorption than other glutathione supplements.

Better Form. Many glutathione supplements use L-glutathione. ProHealth uses S-acetyl glutathione, a derivative of glutathione that is more bioavailable, can cross mitochondrial membranes and can increase glutathione levels inside cells better.

Higher Dose. Typical glutathione supplements contain 100 mg, whereas ProHealth’s S-acetyl glutathione contains 300 mg per serving.

Stability Protection. The use of stomach acid-resistant capsules (DRcaps) further protects glutathione’s stability.

Meets US Pharmacopeia Standards. Our S-acetyl glutathione ingredients meet US Pharmacopeia standards.

Free of Unwanted Ingredients. S-acetyl glutathione doesn’t contain yeast, wheat, gluten, sugar, salt, dairy, eggs, peanuts, tree nuts, fish, shellfish, soy, corn, dye or preservatives.

Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.

Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.

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Customer Reviews

Based on 23 reviews

S-Acetyl Glutathione - 300 mg, 60 capsules

Ga√ętan R.

S-Acetyl Glutathione - 300 mg, 60 capsules

Mario L.

S-Acetyl Glutathione - 300 mg, 60 capsules

christopher h.
great results

excellent trusted company with valuable products. feeling the results of this

Good 4u energy

I feel better daily energy when I take this supplement. Love this product.

Susan E.
ProHealth is the best

Consumer Reports and other external testing labs confirms the quantity and quality of ProHealth products which is why I trust buying this product here.

Andrew w.

excellent product.

good for our health

After taking it, I feel less tired, I think my skin got better, too

ChauYuan C.
Feeling good.

Since I know the benefit of glutathione, I have been taking this for more than a year now.y body feels light and well! Now, everybody in my family is taking this.

Wei C.

S-Acetyl Glutathione (300 mg, 60 Capsules) by ProHealth

Frequently asked questions

This product is suggested for use once or twice per day (in the morning and in the evening), or as recommended by your healthcare provider.
S-Acetyl Glutathione should be taken on an empty stomach.
Keep S-Acetyl Glutathione in a cool, dry place.
S-acetyl glutathione is generally considered safe, but some people may experience cramping or bloating.
L-glutathione is the isomer form of glutathione, while S-acetyl glutathione is a derivative of glutathione. S-acetyl glutathione is more stable in the blood, can cross the mitochondrial membrane and therefore can better increase glutathione levels inside cells.