In a study of over 100,000 people over 30 years, the lowest risk of mortality was seen in adults who exercised over 150 minutes per week, with greater reductions from exercising over 500 minutes.
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The enzyme ADAR1—a specialized enzyme involved in RNA editing— is found to regulate cellular senescence, suggesting potential implications for aging, with the protein p16INK4a being involved.
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The aging microbiome is linked to impaired hippocampal function. Fecal microbiota transplantation from aged donors into young mice triggered profound hippocampal alterations.
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The molecule inosine is capable of burning fat in brown adipose tissue. Brown fat cell activation is positively correlated with cardiometabolic health, as it burns energy as heat rather than storing it.
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