FDA Confirms NMN Is Lawful in Dietary Supplements 

Trigonelline is an NAD-increasing molecule naturally found in coffee, fenugreek, and the human body. Preclinical models show trigonelline increases mitochondrial activity and supports muscle function during aging.

Insulin has been found to regulate the quality control of mitochondria in neurons, which has implications for cognitive health

Healthy and rapid agers had clear differences in their metabolomes, indicating that metabolites in the blood could reflect biological age.