Mice that are engineered to express high levels of the SIRT6 (sirtuin-6) gene show that an increased life expectancy by an average of 30% in both males and females.

A clinical trial finds that diet and lifestyle modifications, like stress, sleep, and exercise, can reduce biological age by over 3 years, as measured by DNA methylation changes.

The plant-derived substance beta-sitosterol, found in avocados, pistachios, almonds and other nuts, reduces anxiety in mice, both on its own and in combination with an antidepressant.

Four weeks of following a low-calorie, ketogenic diet boosted testosterone levels in overweight men, in addition to reducing body weight, fat mass, and Body Mass Index (BMI).