Estrogen deficiency during menopause changes microRNA signaling in skeletal muscle, activating a series of cell-death signaling cascades that are detrimental to muscle mass.

Biodegradable microcapsules encourage the development of new neurons in the hippocampus of the brain by delivering nerve growth factor. If applied to humans, this could reverse many cases of neurodegeneration.

Skeletal muscle plays a role in controlling glucose levels, which is vital for reducing the risk of metabolic diseases like type 2 diabetes. More skeletal muscle has increased activity of a gene called (KLF15).

A genetic analysis of over 250,000 people finds 15 areas of the genome that are associated with muscle weakening with age, which could drive new therapeutic interventions for muscle loss.