Transplants of fecal matter housing gut microbes from young mice reversed age-related changes in the brain, suggesting that the microbiome may be a suitable target to promote healthy aging.

Neuroplasticity, the brain’s ability to adapt and rewire connections, is a key player in maintaining cognitive vitality. Researchers reverse age-related memory loss in mice by targeting compounds involved with plasticity. 

High coffee consumption (more than 6 cups per day) is linked to smaller brains and higher odds for poor brain health, finds a study involving hundreds of thousands of adults.

Superagers that resist cognitive decline show distinct structural and functional changes in their brains, keeping their memory and recall abilities similar to that of 25-year-olds.