NAD+ Triple Boost  with NMN Product Image
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NAD+ Triple Boost  with NMN

90 Capsules • SKU: PH659

Title

The Most Complete NAD+ Formula Ever Developed 

•  Recharges cellular energy at the source*2,3,5,16,17   
•  Supports youthful function in every cell*1-3,5–8,13,16  
•  Helps your body repair and renew itself*1-3    

•  Strengthens the systems that decline with age*1-3,8     

•  Backed by the world’s most advanced NAD+ science*

Title

Triple Lab Tested

Doctor Formulated 

Manufactured in the USA

100-Day Risk-Free Guarantee

Next-Level Synbiotic Support 

A Smarter Way to Optimize NAD+* 

NAD+ is more than a molecule — it’s the spark behind life itself, driving energy production, cellular repair, and resilience across every system of the body. But true NAD+ support goes beyond simply adding precursors. It requires a comprehensive strategy that: 

  • Builds NAD+ through multiple molecular entry points* 
  • Protects NAD+ from depletion and breakdown* 
  • Transforms NAD+ into usable cellular energy* 

That’s the science behind ProHealth’s NAD+ Triple Boost. Using a systems-based approach, it supports every step of the NAD+ lifecycle, helping replenish what aging reduces and delivering whole-body vitality you can truly feel.*1-3,6-8 

Three Ways to Unlock Your NAD+ Potential 

Build: Fuel Every Pathway* 

The body builds NAD+ through several pathways. By providing a broad spectrum of precursors, this formula fuels the most important routes of NAD+ synthesis — helping maintain healthy, youthful levels of this vital coenzyme.* 

  • NMN (Nicotinamide Mononucleotide): A clinically studied vitamin B3 derivative that drives the Salvage Pathway, recycling NAD+ for mitochondrial energy and sirtuin activation.*2,16,17 
  • Vitamin B3 (Niacin & Niacinamide): Dual forms that feed both the Preiss–Handler and Salvage Pathways, the body’s main NAD+ production routes.*7,13 
  • Tryptophan: An essential amino acid that supports serotonin synthesis while fueling the De Novo Pathway to generate NAD+ from scratch.*1,2,7 
  • NMNH (Reduced NMN): A next-generation NAD+ precursor that bypasses rate-limiting steps, producing NAD+ faster and more efficiently.*8 

Protect: Defend Your NAD+ Stores* 

NAD+ can be rapidly depleted by enzymes such as CD38. NAD+ Triple Boost includes compounds that defend your stores, helping to minimize loss and extend NAD+ availability.*  

 

  • Apigenin: A plant flavonoid that supports the preservation of NAD+ by targeting CD38, an enzyme that naturally consumes NAD+.*4 

Transform: Turn NAD+ Into Energy* 

Optimal NAD+ levels are only part of the equation. Your cells must efficiently use NAD+ to power critical enzymes and pathways related to aging and cellular health.*   

  • B Vitamins (including methyl-folate and methyl-B12): Essential cofactors for ATP generation and methylation, important for energy metabolism and the recycling of NAD+ breakdown products.*9-12   
  • Stilbenoids (Resveratrol, Pterostilbene, & Piceatannol): Powerful polyphenol compounds that boost the activity of sirtuins — a family of enzymes that use NAD+ to fuel their activity.  By activating sirtuins, these compounds help amplify the benefits of increased NAD+ levels.*14,15   

How it Works

Your All-in-One NAD+ System 

Triple-Pathway Innovation: Fueling 3 Vital Routes to NAD+ 

NAD+ Triple Boost isn’t just another supplement; it’s a comprehensive system designed to work with your body’s natural biology. By combining multiple proven precursors, plant compounds, and essential cofactors, it supports NAD+ at every stage of its lifecycle. The result is a formula that not only helps restore youthful NAD+ levels but also preserves them and channels them into real cellular energy. It’s a complete, science-driven solution for those who want to stay energized, resilient, and strong as they age.*1-3,5-8,13,16,17 

The ProHealth Difference

The ProHealth Difference

Doctor Formulated

Created by our in-house science team to support multiple aspects of healthy aging.*

Triple Lab Tested

Verified three times by independent labs for purity and potency. 

View Certificate of Authenticity

USA Manufacturing Excellence

Produced in FDA-regulated, GMP-certified facilities since 1988.

Confidence In Every Bottle

Confidence In Every Bottle

100-Day Risk-Free Guarantee

We stand behind our products. If you're not satisfied please reach out to our Santa Barbara, CA office for a full refund within 100 days — no hassle, no questions.

Complete Transparency

In a market crowded with questionable supplements, we set ourselves apart by publishing third-party lab test results. We're commited to full transparency —so you know exactly what's in every bottle.

Free Shipping

Whether you're a first-time or returning customer, we offer free U.S. shipping on orders over $30 — making your shopping experience even easier and more convenient.

Advancing Health & Longevity 
since 1988

Founded in 1988, ProHealth has been trusted by those who want more out of life — more energy, more vitality, and more years lived well. We are the global leader in NAD+ support, offering the world’s most comprehensive collection of NAD+ boosters. Beyond NAD+, our wide range of products features clinically studied ingredients and advanced formulations designed to address the 12 hallmarks of aging. 

 

Prohealth’s uncompromising commitment to quality has earned the trust of health seekers, researchers and practitioners alike. Doctor-formulated, triple lab tested, and backed by a 100-day guarantee, Prohealth’s next-generation supplements are built to keep you unstoppable. 

Pioneering Longevity 

Since 1988 

No company offers a broader or more advanced range of NAD+ solutions than ProHealth. From foundational ingredients like NR and NMN to next-generation compounds such as NMNH and Apigenin, our collection spans every major pathway of NAD+ production. With diverse delivery forms, clinically studied ingredients, and formulations that address energy, brain function, metabolism, and longevity, ProHealth stands as the global leader in NAD+ innovation — trusted by researchers, practitioners, and health seekers worldwide.* 

Meet Our Ingredients

Nicotinamide Mononucleotide (NMN)

A clinically studied form of vitamin B3 that supports the NAD+ salvage pathway, helping replenish cellular NAD+ levels efficiently.*   

Tryptophan

An essential amino acid that feeds the De Novo NAD+ pathway.*  

Apigenin

A plant-based flavonoid that helps preserve NAD+ levels by targeting CD38, an enzyme known to degrade NAD+ in the body.*  

B Vitamins

Includes methylated and bioactive B vitamins that support mitochondrial energy production and provide methyl groups crucial for NAD+ metabolism.*  

Magnesium

A vital cofactor required for enzymatic reactions in NAD+ synthesis and ATP production, supporting optimal cellular energy function.*    

Resveratrol

A polyphenol that activates sirtuins —NAD+ dependent enzymes linked to longevity, cellular repair, and healthy aging.*  

Pterostilbene

A powerful polyphenol related to resveratrol, known for its superior bioavailability and ability to activate sirtuins, support antioxidant defenses, and promote healthy NAD+ metabolism.* 

NMNH (Reduced NMN)

A next-generation NAD+ precursor that bypasses key rate-limiting steps to support faster, more efficient NAD+ production through an alternative biochemical pathway.*

Piceatannol

A naturally occurring stilbenoid that supports healthy inflammation signaling and may complement sirtuin activation and cellular resilience mechanisms.*  

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.    

 

A Word from Our Chief Science Officer 

“The NAD+ ecosystem isn’t a single switch. It is a dynamic, ever-evolving network of pathways, feedback loops, and cellular compartments that change with age. That’s why NAD+ Triple Boost was built to go beyond simple replenishment. By targeting multiple control points across the entire NAD+ system, we’re helping the body unlock its full regenerative potential. This is truly a smarter, more complete approach to NAD+ optimization.” 

Frequently Asked Questions

Frequently Asked Questions

Frequently Asked Questions

Do I need a subscription?  

No, a subscription isn’t required. You’re always welcome to make a one-time purchase. Subscriptions are simply available for extra convenience and savings.  

How do I cancel my subscription?  

You’re free to cancel anytime with no commitments or fees. Just log into your account, go to “My Account,” and select “Manage Subscriptions.” From there, you can remove or cancel products directly.  

What is your refund policy?  

We offer a 100-day, risk-free guarantee. If you’re not fully satisfied with your purchase, simply contact us for a complete refund—no hassle, no questions asked. 

What can I expect to feel when taking NAD+ Triple Boost?  

NAD+ works primarily at the cellular level, so the benefits are not always outwardly apparent. That said, many people report experiencing greater energy, sharper focus, and better exercise performance.*  

How quickly can I expect results?  

Results can vary based on a variety of factors, but many people report noticing benefits within 2–4 weeks of consistent daily use.*  

Can you use NAD+ Triple Boost every day?  

Yes. NAD+ boosters are designed for daily use, and consistency is key to supporting healthy NAD+ levels. Taking them each morning helps establish a routine and provides steady support for cellular energy, repair, and overall vitality throughout the day.*  

Why does NAD Triple Boost have so many ingredients?   

Because NAD+ is so essential, the body uses multiple pathways to make it. This formula provides key ingredients to support each of those pathways.*  

Does NAD+ Triple Boost cause flushing?  

Our formula includes a small amount of nicotinic acid (niacin), which can sometimes cause brief flushing (warmth, redness, or tingling), especially on an empty stomach. The dose is below the level where flushing usually occurs, but it’s still possible. The other forms of B3 in this formula — niacinamide and nicotinamide riboside/mononucleotide — do not cause flushing.  

What’s the difference between NR, NMN, and NMNH?  

All three are NAD+ precursors that help raise NAD+ levels. NR and NMN are well-studied with strong safety and human data, while NMNH is a newer form that may boost NAD+ more quickly, though research is still emerging. Each follows slightly different pathways, offering options based on your goals.*  

How does NAD+ Triple Boost compare to NAD+ IV therapy?  

NAD+ Triple Boost is a supplement that supplies precursors to support your body’s own NAD+ production inside cells. NAD+ IV therapy delivers NAD+ directly into the bloodstream, primarily boosting levels outside the cells.*  

Customer Reviews

Based on 5 reviews
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J
Jennifer T.
Excellent Product

Highly recommend for women over 40!

R
Rene O.

NAD Triple Boost™  with NMN - 90 capsules

G
Gentry G.
Game Changer!

I've worked with numerous NAD precursors & NMN products so deliberately gave this formula some time to track the effects on my overall system. I'm definitely experiencing increased energy & less inflammation throughout the body. Going forward...I'll keep this one in my daily stack.

Y
Y G.

Hopefully is not a placebo but I am really liking them

J
Jeremy C.
Complete NAD+ Formula

Stoked to be unlocking my NAD production potential.

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References

References

1Conlon N et al. Biochem Pharmacol. 2022;198:114946.   

2Rajman L et al. Cell Metab. 2018;27(3):529-547.    

3Xie N et al. Signal Transduct Target Ther. 2020;5(1):227.   

4Kramer DJ et al. Front Nutr. 2024;11:1359176.  

5Membrez M et al. Nat Metab. 2024;6(3):433-447.  

6Nadeeshani H et al. J Adv Res. 2021;37:267-278. 
7Palmer RD et al. Aging Med (Milton). 2021;4(3):214-220.

8Song Q et al. Adv Nutr. 2023;14(6):1416-1435. 

9Oregon State University - Linus Pauling Institute. Magnesium. Accessed July 26, 2024. https://lpi.oregonstate.edu/mic/minerals/magnesium.     

10National Institutes of Health. Magnesium Fact Sheet for Health Professionals. Accessed July 26, 2024. https://ods.od.nih.gov/factsheets/Magnesium-HealthProfessional.    

11Dominguez LJ et al. Nutrients. 2024;16(4):496.  

12Barbagallo M et al. Magnes Res. 2009;22(4):235-246.  

13Freeberg KA et al. J Gerontol A Biol Sci Med Sci. 2023;78(12):2435-2448.   

14Briskey D and Rao A. Pharmaceutics. 2020;12(12):1190.   
15Wei Y et al. Int J Biol Macromol. 2024;270:132026.  

16Yang X et al. Food Front. 2025;6(2):630-643. 

17Rahman SU et al. Aging Dis. 2024;15(2):565-583.