S-Acetyl Glutathione - 300 mg, 60 capsules

SKU: PH497

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Supports Natural Antioxidant Activity*

  • Supports healthy cell function and healthy aging
  • Supports amino acid transport across cell membranes
  • Stomach acid-resistant capsules for stability protection

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Supplement Facts
Serving Size: 1 Capsule
Servings Per Container: 60
Amount Per Serving %DV
S-Acetyl Glutathione (Emothion™) 300 mg *
* Daily Value not established
  • Other Ingredients: HPMC (acid-resistant vegetarian capsule), microcrystalline cellulose, magnesium stearate.
  • Suggested Use: Take one capsule, one to two times daily on an empty stomach or as directed by your healthcare professional.
  • Warning: Do not eat freshness packet. Keep in bottle.
  • Note: Store in a cool, dry place

Glutathione functions extensively in tissues and organs throughout the body. It plays critical roles in protecting the body from oxidative stress, maintaining cellular functions, and supporting healthy immune function. [1,4] Many factors can increase cellular exposure to oxidative insult, and therefore increase cellular consumption of nutrients - such as glutathione - that provide antioxidant activity. This may result in a fierce cycle of oxidative stress and challenges to detoxification. Complete biotransformation and protection from oxidative stress are important to maintaining cellular integrity and tissue health. *[2,5]

Other Benefits of Maintaining Healthy Glutathione Levels

Much information related to mitochondrial health has surfaced in scientific literature. Mitochondria, the energy-producing powerhouses of cells, are also the primary intracellular site of oxygen consumption and the major source of reactive oxygen species (ROS).

S-acetylglutathione has been shown to cross the membrane of the mitochondria, increasing the organelle's activity and minimizing ROS.[8,9] Reduction of ROS is associated with maintaining mitochondrial integrity and function, and improved mitochondrial health is believed to support overall health and energy. Use of stomach acid-resistant capsules (DRcaps) further protect stability. Laboratory data showed that S-acetyl glutathione increased intracellular glutathione and had a positive effect on many oxidative stress biomarkers.*


  1. Locigno R, Pincemail J, Henno A, et al. Int J Oncol. 2002 Jan;20(1):69-75. [PMID: 11743644]
  2. Lomaestro BM, Malone M. Ann Pharmacother. 1995 Dec;29(12):1263-7
  3. [PMID: 8672832]
  4. Vogel J, Cinatl J, Dauletbaev N, et al. Med Microbiol Immunol. 2005 Jan;194(1-2):55-59. [PMID: 1462435]
  5. Ballatori N, Krance SM, Notenboom S, et al. Biol Chem. 2009 Mar;390(3):191-214. [PMID: 19166318]
  6. Anderson ME, Nilsson M, Sims NR. Neurochem Int. 2004 Feb;44(3):153-59. [PMID: 14568558]
  7. Kretzschmar M. Exp Toxicol Pathol. 1996 Jul;48(5):439-46. [PMID: 8765689]


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Customer Reviews

Based on 17 reviews
Andrew w.

excellent product.

good for our health

After taking it, I feel less tired, I think my skin got better, too

ChauYuan C.
Feeling good.

Since I know the benefit of glutathione, I have been taking this for more than a year now.y body feels light and well! Now, everybody in my family is taking this.

Wei C.

S-Acetyl Glutathione (300 mg, 60 Capsules) by ProHealth

Magdalena G.

I’m in my gut healing journey and S Acetyl Glutathione is one of the must have to achieve my goal!

george c.

Quality product

H. P.
Pre-formed glutathione

I choose this product because of its high-quality origins— a German manufacturing process— and its unique high-absorption, water-soluble form. It is pre-formed and does not depend on body-conversion of a substrate such as NAC. Therefore I feel comfortable that it supplements the body’s additional need for glutathione when it is under stress.

Andres M.

It works fantastically. I use it when I feel tired, and it helps a lot, no doubt.

joel w.
just the right product for my needs

I've been taking liposomal glutathione but understand that S-Acetyl Glutathione is up-regulated on the cellular level better and has an improved absorption rate. The 300 milligrams is triple the usual 100mg sold on the supplement market. What a great deal for four months supply. Joel Whitfield

Faye E.
Great product. I've taken it

Great product. I've taken it for years. Highly recommend it.

Frequently asked questions

This product is suggested for use once or twice per day (in the morning and in the evening), or as recommended by your healthcare provider.
S-Acetyl Glutathione should be taken on an empty stomach.
Keep S-Acetyl Glutathione in a cool, dry place.
S-acetyl glutathione is generally considered safe, but some people may experience cramping or bloating.
L-glutathione is the isomer form of glutathione, while S-acetyl glutathione is a derivative of glutathione. S-acetyl glutathione is more stable in the blood, can cross the mitochondrial membrane and therefore can better increase glutathione levels inside cells.