In aged mice, NMN supplementation improved neurovascular function by promoting sirtuin activation and mediating genes involved in mitochondrial rejuvenation.

Oligodendrocytes are cells that make myelin (the protein that covers and protects neurons) and are required for long-term memory but reduce with age. In mice, restoring the production prevents memory loss.

Transcendental Meditation led to reduced stress and anxiety and improved feelings of well-being, due to structural changes in the brain that play an important role in modulating emotions.

Patients with gum disease were twice as likely to have a stroke caused by hardening of large arteries within the brain than those without gum disease.