The community important factors that lowered life expectancy were more fast food restaurants, higher population density, and more jobs in mining, quarrying, and oil/gas extraction.

People who ate a low-carb diet (no sugar, grains, rice, or starchy vegetables) for one week had a more stable brain network, likely due to the brain using ketones rather than glucose for fuel.

Excess visceral abdominal fat causes inflammatory proteins (interleukin-1 beta) to cross the blood-brain barrier, leading to over-activated microglia (which are usually protective) and impaired cognition.

Caloric restriction, even starting at later age, can prevent cellular aging. 57% of the cellular age-related changes that were found in rats on a normal diet were not seen in 30%-calorie-restricted rats.