The APOE4 gene is a major risk factor for Alzheimer's disease due to its involvement in developing proteins that cause dementia. This study is the first to link APOE4 with tau protein aggregation.

Type 2 diabetics who lost weight successfully reversed the condition during a 2-year study. Excess fat in the liver and pancreas switches off genes that direct how insulin should be produced.

Targeted genetic screening of men who are at higher risk of prostate cancer could prevent 1 in 6 deaths by being able to better detect harmful cancers that are missed from PSA testing.

Working 49 hours or more per week in an office was linked to a 66% increased risk of high blood pressure. The lowest risk was with employees who worked fewer than 35 hours weekly.