Longevity Articles

NADH and Green Tea: A Dynamic Duo for Energy and Longevity

NADH and Green Tea: A Dynamic Duo for Energy and Longevity
It’s well-known that older adults tend to have less energy than they did when they were younger. But it doesn’t necessarily have to be that way—as many of the causes of low energy stem from the loss or decline of various compounds inside our bodies, supplementing with them can help. 

One of these compounds is NADH, a reduced form of the vital compound NAD+, which has been found to support energy levels and mental clarity with age. Another factor affecting both energy and longevity is weight gain, which also creeps up with increasing age. Combining NADH with green tea extract is a great way to combat these common age-related symptoms, leading to boosted energy, healthier body weights, and longevity support.

Why We Need NADH for Energy

The compound NAD+ is necessary for both healthy aging and life as a whole, as NAD+ facilitates the creation of cellular energy. We also need NADH, a compound chemically similar to NAD+ that acts a little differently in the body. Both NAD+ and NADH are vital for producing cellular energy in the form of ATP—in fact, each molecule of NADH produces three molecules of ATP.

Despite its necessity, ATP production can gradually decline with age, partly because molecules like NAD+ and NADH see similar reductions as we grow older. With this drop in NADH levels comes a subsequent decrease in ATP production, leading to symptoms like low physical and mental energy. Therefore, adding NADH supplements to your daily routine can help to bolster ATP production, which supports energy levels, mood, and mental focus as we age.

One clinical study found that those who supplemented with 20mg of NADH experienced significant reductions in anxious feelings and heart rate after stress tests. Another study found that people who took 20mg of NADH (combined with 200mg of the antioxidant Coenzyme Q10) for eight weeks significantly reduced their total fatigue scores and boosted cellular measures of NAD+/NADH ratios and ATP production.

NADH and Green Tea: A Dynamic Duo for Energy and Longevity

How Green Tea Supports Longevity

Green tea contains a compound called EGCG (epigallocatechin gallate), which has been found to have 25-100 times more antioxidant power than vitamins A, C, and E. The high antioxidant content of green tea and compounds like EGCG can help to protect the body against damage from oxidative stress—a buildup of harmful molecules that accelerate aging and disease.

The polyphenols in green tea, especially EGCG, have also been shown to induce autophagy, which is the internal recycling process that removes damaged or toxic cells to improve overall health and increase longevity.

Research has found that drinking green tea is linked to longer lifespans, as seen in a study of over 100,000 Chinese adults. Those who habitually drank tea three times per week or more had a 1.26-year increase in life expectancy compared to those who never drank tea or drank it less than three times per week.

A similar relationship was found in Mediterranean adults, in which Greek adults over age 50 who consumed green tea had a higher “successful aging index” (SAI), which uses a scale of 10 factors related to a healthy aging process.

In research with animals, EGCG consumption significantly extended the lifespans of mice, with those receiving EGCG having a 46% lower risk of death than control mice. The researchers speculated that these improved survival rates were likely due to EGCG’s senolytic qualities—the ability to clear out harmful senescent cells. Compared to young mice, aging mice steadily accumulated DNA damage and senescence markers, while EGCG consumption attenuated these age-related responses.

Green tea extract may also contribute to longevity and increased energy by helping with weight loss. This may be due to the combination of catechins, like EGCG and caffeine, having a thermogenic effect. When this happens, the body is more effective at burning calories and fat. These effects may be attributable more to the catechins than the caffeine.

One study found that men who consumed a green tea extract (containing 50mg caffeine and 90mg EGCG) three times during the day had a significant increase in 24-hour energy expenditure compared to those who just consumed the 50 mg of caffeine, indicating that the EGCG provides additional thermogenic effects in this study and may help with weight loss.

drinking green tea for longevity

Combining NADH and EGCG

Adding NADH and green tea extract (EGCG) to your daily regimen may support energy levels and weight loss, which can both decrease with age—and supplements like Energy NADH and Green Tea EGCG Extreme may be able to help.

With 12.5mg of NADH and 390mg of EGCG, these supplements are a dynamic duo for fighting age-related cellular damage and supporting healthy energy levels at any age.

References:

Alegre J, Rosés JM, Javierre C, Ruiz-Baqués A, Segundo MJ, de Sevilla TF. Nicotinamide adenine dinucleotide (NADH) in patients with chronic fatigue syndrome. Rev Clin Esp. 2010;210(6):284-288. doi:10.1016/j.rce.2009.09.015

Castro-Marrero J, Cordero MD, Segundo MJ, et al. Does oral coenzyme Q10 plus NADH supplementation improve fatigue and biochemical parameters in chronic fatigue syndrome?. Antioxid Redox Signal. 2015;22(8):679-685. doi:10.1089/ars.2014.6181

Dulloo AG, Duret C, Rohrer D, et al. Efficacy of a green tea extract rich in catechin polyphenols and caffeine in increasing 24-h energy expenditure and fat oxidation in humans. Am J Clin Nutr. 1999;70(6):1040-1045. doi:10.1093/ajcn/70.6.1040

Naumovski N, Foscolou A, D'Cunha NM, et al. The Association between Green and Black Tea Consumption on Successful Aging: A Combined Analysis of the ATTICA and MEDiterranean ISlands (MEDIS) Epidemiological Studies. Molecules. 2019;24(10):1862. Published 2019 May 15. doi:10.3390/molecules24101862

Sharma R, Kumar R, Sharma A, Goel A, Padwad Y. Long-term consumption of green tea EGCG enhances murine health span by mitigating multiple aspects of cellular senescence in mitotic and post-mitotic tissues, gut dysbiosis, and immunosenescence. J Nutr Biochem. 2022;107:109068. doi:10.1016/j.jnutbio.2022.109068

Wang X, Liu F, Li J, et al. Tea consumption and the risk of all-cause mortality: The China-PAR project. Eur J Prev Cardiol. 2020;27(18):1956-1963. doi:10.1177/2047487319894685



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