A lifestyle intervention program including diet, sleep, exercise, relaxation guidance, and probiotics reduced participants' biological age by over three years. 

In the first human trial of its kind, NMN improved several markers of glucose metabolism that are commonly dysregulated in people with obesity, prediabetes, or type 2 diabetes.

With this research that spans multiple species, from mice to flies to humans, the compound spermidine shows promise for supporting cognition with age.

Researchers find that diet quality and intake of cocoa flavanols — plant-based, health-supporting antioxidants found in chocolate — may benefit age-related memory function in normal cognitive aging.