B-12 Extreme™ - 35000 mcg, 30 lozenges

High-potency vitamin B12 supports energy, cellular health, detoxification and mental acuity.

• For energy, mental acuity, cellular health, liver support and detoxification
• Provides high doses of all four forms of vitamin B12
• Includes the only two biologically active forms of vitamin B12 without requiring conversion (methylcobalamin and dibencozide).

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Supports Energy Levels. Dibencozide (also known as adensylcobalamin) metabolizes essential fatty acids to produce more energy. As a biologically active form of B12, this dibencozide reacts with cells to provide muscles and nerves with bursts of energy. Research shows that people with vitamin B12 deficiency are more likely to experience severe fatigue.¹

Supports Cellular Health and DNA. Vitamin B12 plays a significant role in red blood cell and DNA synthesis. Methylcobalamin plays a vital part in cell growth, while cyanocobalamin creates enzymes to help the body with blood formation, cell reproduction and tissue synthesis.²

Supports Healthy Cognitive Function. Methylcobalamin is important for the central nervous system. This form of vitamin B12 helps to promote healthy homocysteine levels, increase the brain's focus and mental clarity, and supports the spinal cord's function.^3,4

Supports Detoxification and Liver Health. The second phase of liver detoxification uses vitamin B12 to transform toxic intermediary compounds into harmless compounds to be excreted. Cyanocobalamin, the most common of the cobalamins, becomes metabolically active in your liver, and the hydroxo version helps support overall detoxification.⁵

References:

1. Huijts M, Duits A, Staals J, van Oostenbrugge RJ. Association of vitamin B12 deficiency with fatigue and depression after lacunar stroke. PLoS One. 2012;7(1):e30519. doi:10.1371/journal.pone.0030519

2. Allen LH. Vitamin B-12. Adv Nutr. 2012;3(1):54-55. doi:10.3945/an.111.001370

3. Tardy AL, Pouteau E, Marquez D, Yilmaz C, Scholey A. Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence. Nutrients. 2020;12(1):228. Published 2020 Jan 16. doi:10.3390/nu12010228

4. Garrod MG, Green R, Allen LH, et al. Fraction of total plasma vitamin B12 bound to transcobalamin correlates with cognitive function in elderly Latinos with depressive symptoms. Clin Chem. 2008;54(7):1210-1217. doi:10.1373/clinchem.2007.102632

5. Hodges RE, Minich DM. Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived Components: A Scientific Review with Clinical Application. J Nutr Metab. 2015;2015:760689. doi:10.1155/2015/760689