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Methylfolate Featuring Quatrefolic - 15 mg, 60 capsules

SKU: PH489

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$49.99

Regular price $34.99
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Free Nutritional Advisor

Free Nutritional Advisor

Supports healthy aging, improves heart health, supports cognitive health

  • Provides methylation support
  • Supports healthy homocysteine levels
  • May help improve fertility and infertility success rates

View Certificate of Analysis »

Research-Supported Benefits:

Reduces Menopause Symptoms. Hot flashes are a common occurrence in menopausal women. Folate is shown to help reduce hot flashes compared to women don’t supplement. 1

Supports Heart Health. High homocysteine levels can increase the risk of developing heart-related health concerns. Folate has been shown to support healthy homocysteine.2

Supports Cognitive Health. Folate absorption has been shown to decrease with age which can impact cognitive function. Additionally, high homocysteine levels have also been shown to impact brain health. Folate supplementation can encourage cognitive health with age.3-6

Provides Fertility Support. Folate supplementation has been linked with improved fertility outcomes. Additionally, it has been shown to support folate absorption in individuals who have a methylation issue which can impact fertility.7

Supports Healthy Aging. Low levels of folate have been associated with an increased risk of disease. Supplementation can help improve folate levels and reduce the risk of age-related health issues.8, 9

References:

1. Bani Soheila, J Caring Sci 2013

2. Mazza A. et al. Biol Regul Homeost Agents 2016 

3. Rima Obeid R., Herrmann W. FEBS Letters 580, 2006

4. Stover Patrick, Curr Opin Biotechnol 2017 

5. Seshadri S. at al. N Engl J Med 2002  

6. Bottiglieri T, J Neurol Neurosurg Psychiatry 2000 

7. Thaler C.J. 2014 

8. Stover PJ. Modern Nutrition in Health and Disease 2012 

9. Tinelli C, Di Pino A Front. Nutr. 2019 

  • ProHealth's Methylfolate with Quatrefolic® supports a variety of bodily functions including healthy mood, memory, circulation and well-being.* Folic acid and also food folate are not biologically active and need to be converted to the metabolically active 5-methyltetrahydrofolate (5-MTHF) through a multi-steps process where the enzyme methylenetetrahydrofolate reductase (MTHFR) owns a key role.
  • Quatrefolic® provides 5-methyltetrahydrofolate (MTHF), the active form used by the body for DNA regulation and other fundamental metabolic processes. While maintaining the same biological properties of 5-MTHF, Quatrefolic® has been able to increase stability, bioavailability and solubility over other previous folate generations.
Supplement Facts
Serving Size: 1 capsule
Servings Per Container: 60
Amount Per Serving %DV
Folate (as Quatrefolic® (6S)-5-Methyltetrahydrofolate, glucosamine salt) 15 mg 3,750%
* Daily Value (DV) based on a 2,000 calorie diet.
    REV. 01.21
  • Suggested Use: Take 1 capsule daily or as directed by your healthcare professional.
  • Storage: Store in a cool dry place. Keep out of reach of children.
  • Contraindications: Doses of 5 mg or higher per day can cause abdominal cramps, diarrhea, and rash.
  • Caution: If you are pregnant or nursing, consult your physician before using this product. 
  • Other Ingredients: Microcrystalline cellulose, vegetarian cellulose capsule.

Best Form of Folate. Quatrefolic® is the glucosamine salt of (6s)-5-methyltetrahydrogolate and is comparable to folic acid, the natural form present in the body.

Better Absorption. The active form in Quatrefolic® is more absorbable compared to other brands.

Higher Dosing. Compared to other folate products on the market, Methylfolate contains 3,750% of the Daily Value for folate per serving.

Quality-Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.

Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificate of Analysis is available.

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Customer Reviews

Based on 18 reviews
72%
(13)
22%
(4)
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6%
(1)
C
CC415
Quality Product

Subjectively, I do believe this helps with mood

J
Julianne E.
Happy with this product

A good quality methyl folate at a reasonable price.

S
Steve J.

I've had methylfolate prescribed to me for quite a while, and for me, Quatrefolic seems to work best. Ouatrefolic is somewhat hard to find, and the prices here as good as I've found.

M
Michelle P.

I was reluctant to take 15mg of the quatrofolate but it has helped tremendously. Also the price is the best.

P
Pietro B.
Has been working great for me.

Before taking methylfolate I had air hunger (just couldn't get enough air) and my blood work showed my mcv and mch just outside of high limit and I was always depressed. Now after taking this methyl folate I have no more air hunger nor am I depressed anymore. This particular type of methylfolate from glucosamine salt works much better than other brands that use calcium salt. This has changed my life and I'm so grateful. I just wish pro health would come out with a 7.5mg dosage so I can take it in the morning and evening.

C
Chris S.
Works Well

Getting improved spirits

J
Jen F.
15mg may be too high for some people

Not the product's fault, but this dose is too high for me and resulted in some GI cramping. Will be trying a smaller dose.

M
Margaret K.
It is what it says it is

This is one of those things where, depending on what you're taking it for, it's hard to tell if it's working or not. But it seems things are worse when I don't take it. I have ordered from ProHealth multiple times and plan to keep returning for this vitamin.

P
Pam E.
Saving Money and Healthy

My doctor wanted me to take L-Methylfolate 15mg daily with my Prescription medication. I was looking online to save money when I needed to reorder. ProHealth came up as #1 recommend with more benefits,
but didn't have the L in front. I called and representative couldn't give me Medical advice, but sent me detailed data so I could show my doctor and get her approval. I saw her that week and she approved highly. So I am spending less while getting more benefits and I feel great!

J
Judi G.
Good for your brain

I was told by a psychiatrist that Methylfolate would be a good addition to my diet. I found it on Pro Health a month ago and am happy with how it lifts my spirits.
You can get Folic Acid at a cheaper price,but it doesn't do the job. This is a quality product.

Frequently asked questions

Take 1 capsule daily or as directed by your healthcare professional.
Folate is the natural form of vitamin B9 and folic acid is the synthetic form.