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Brain Health
Heart Health
DNA Health
Blood Sugar SupportFree Nutritional Advisor
Free Nutritional AdvisorHelps combat aging, improves heart health and promotes muscle strength
- NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight and gene expression.
- Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+.
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Supports Longevity. Studies have shown that boosting NAD+ synthesis in the body extends the lifespan of yeast, worms and flies. (1)
Blood Sugar Regulation. As we age, we have more trouble processing glucose, leading to higher blood sugar. Supplemental NMN is shown to improve several markers of skeletal muscle glucose metabolism that are commonly dysregulated in people with metabolic disorders. (2)
Supports Metabolism and Healthy Weight. Although excessive body weight can develop at any age, adults over age 40 are particularly susceptible to age-related weight gain as metabolism slows down and body composition is altered to favor fat over lean muscle. As obese individuals have reductions in both NAD+ levels and ATP (energy) production, replenishing NAD+ through NMN can help to reverse this while improving metabolic pathways to maintain a healthy weight. (3,4,5)
Supports Healthy Cognition: Declining cognitive function with age is related to a reduced NAD+ levels that impair mitochondrial function. Replenishing NAD+ stores through NMN may be able to prevent this dysfunction. (6,7)
Supports Healthy Skin: In our 30s and 40s, the appearance of our skin can start to show signs of age. Several studies have examined how boosting NAD+ levels in the skin prevents premature skin aging or supports a healthier external appearance. (8,9)
References:
1. Fang EF, Kassahun H, Croteau DL, et al. NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. Cell Metab. 2016;24(4):566-581. doi:10.1016/j.cmet.2016.09.004
2. Feng Z, Qin Y, Huo F, et al. NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury. Biochim Biophys Acta Mol Basis Dis. 2022;1868(1):166287. doi:10.1016/j.bbadis.2021.166287
3. Gopi S, Balakrishnan P. Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid (vitamin C) and their enhanced bioavailability. J Liposome Res. 2021;31(4):356-364. doi:10.1080/08982104.2020.1820521
4. Katayoshi T, Nakajo T, Tsuji-Naito K. Restoring NAD+ by NAMPT is essential for the SIRT1/p53-mediated survival of UVA- and UVB-irradiated epidermal keratinocytes. J Photochem Photobiol B. 2021;221:112238. doi:10.1016/j.jphotobiol.2021.112238
5. Kim M, Seol J, Sato T, Fukamizu Y, Sakurai T, Okura T. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients. 2022;14(4):755. Published 2022 Feb 11. doi:10.3390/nu14040755
6. Kiss T, Nyúl-Tóth Á, Balasubramanian P, et al. Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. Geroscience. 2020;42(2):527-546. doi:10.1007/s11357-020-00165-5
7. Liao B, Zhao Y, Wang D, Zhang X, Hao X, Hu M. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. J Int Soc Sports Nutr. 2021;18(1):54. Published 2021 Jul 8. doi:10.1186/s12970-021-00442-
8. Mills KF, Yoshida S, Stein LR, et al. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016;24(6):795-806. doi:10.1016/j.cmet.2016.09.013
9. Tarantini S, Valcarcel-Ares MN, Toth P, et al. Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019;24:101192. doi:10.1016/j.redox.2019.101192
10. Wang X, Hu X, Yang Y, Takata T, Sakurai T. Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death. Brain Res. 2016;1643:1-9. doi:10.1016/j.brainres.2016.04.060
11. Yoshino J, Mills KF, Yoon MJ, Imai S. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011;14(4):528-536. doi:10.1016/j.cmet.2011.08.014
12. Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. doi:10.1126/science.abe9985
| Supplement Facts | ||
|---|---|---|
| Serving Size: 2 Capsules | ||
| Servings Per Container: 30 |
||
| Amount Per Serving | %DV | |
| Uthever® β-Nicotinamide Mononucleotide (NMN) |
1000 mg | † |
| † Daily Value (DV) not established | ||
Uthever® is a trademark of EffePharm (Shanghai) Co., Ltd.
- OTHER INGREDIENTS: Hypromellose (capsule), rice flour.
- SUGGESTED DAILY USE: Take two (2) capsules per day, with or without food, preferably in the morning.
- CAUTION: For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place after opening.
- Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+.
- NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight and gene expression.
- NMN Pro 1000 capsules provide maximum absorption by focusing delivery into the small intestine's Slc12a8 NMN transporter sites, where NMN absorption is increased over 100 times.
- Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+.
- NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight and gene expression.
- NMN Pro 1000 capsules provide maximum absorption by focusing delivery into the small intestine's Slc12a8 NMN transporter sites, where NMN absorption is increased over 100 times.
- Only Clincially-Proven NMN. ProHealth’s NMN is the only clinically-proven NMN to boost NAD+ levels in a peer-reviewed, double-blind, placebo-controlled, published, clinical study. Results of the study indicated a 38% increase in NAD+ levels and 12-year reversal in biological age.
- Unique Delivery Method. NMN Pro 1000 focuses on delivery into the small intestine’s Slc12a8 transporter sites, where absorption is maximized and is increased over 100 times, greatly enhancing bioavailability.
- Solvent-Free. Compared to other NMN products, ours is made without any chemical solvents.
- Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.
- Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.
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Legitimately Good
"I am very happy! There are very few NMN products that have been independently tested in a sea of fake products on the web. At least two organizations, including the leading consumer reporting magazine, have verified the ingredient and the claimed content."
Lawrence B. - Verified ProHealth Longevity Customer
NMN gives me the energy of a 30yr old, and I feel I look much younger than my 58yrs
If it does what it claims to do I’ll be ordering for a long time.
This product has increased my cardio vascular endurance in swimming and biking.
Hey everybody, I just wanted to thank ProHealth Longevity for their version of NMN. I've noticed subtle returns daily when supplementing around 900 mg. At the same time, these subtle returns if you will, are Paramount to our bodies with the knowing everyone's body chemistry is independent to themselves.
That said, I read a lot of research and not understanding why PHL as a company doesn't receive the publicity as to how much they are in integrity with all the supplements available they sell.
I'm 58 years old, and have put my body through a lot, and absolutely no boasting, however I must let folks know that I don't even enjoy telling people my age because they simply do not believe it.
All that to say ProHealth Longevity is truly an amazing company, and something tells me they have a quiet confidence, and do not have to subscribe to these websites that I'm sure ask for money to show the world they're the best, when most likely they're not.
That's what I respect so so much about this company, as they don't have to brag because they have a knowing that their products are manufactured properly with a ton of testing, and taking it as far as truly having a third party company testing their products as well.
Thank you so much for all you do, and continue flying under the radar, because manufacturing the best products is more important than telling the world I'm the best.
Love it, you guys are fabulous and I will continue using you all as long as I'm absolutely able
🌟🌟🌟🌟🌟
I have really been loving this product. I am feeling more energy than normal and feeling pretty good on it. I feel like it is a very worthwhile supplement to be on.
Take two capsules 500mg a day, full of energy
I am so happy that I have discovered this product.
It is really giving me an advantage and assisting me as a health care worker and athlete.
I do a lot of research reading and find this product nearly perfect.
As a 57 years young female I started taking this to see if I could notice any difference in my skin or health. After a month I definitely notice no “afternoon crash”- I can stay on task be it mental or physical and continue productivity as I had hours earlier. Highly recommend! 👏🏼
I discovered this product via a Dr Gundry podcast.
I started off with the highest dose which was probably a little too strong for me,my energy skyrocketed.
I am a physical therapist so I really need my energy and body to be on point.
The pro 500 really seems to be working for me.I just bought a 3 month supply.My go to product was Carbon 60 by Bob Greska but I think that NMN is what I need.
I purchased this product because I was feeling sluggish and not sleeping well. After using for a month, I feel better than I have in months. My sleep is much better and I definitely have more energy. I can even see more muscle definition after my workouts. I am very happy with the product. If you are feeling like I was, lets try!! it worked for me!
Excellent product
This is my third time to repeat order for Prohealth NMN PRO 300. My family members in Hong Kong all changed to use Prohealth NMN products after trial. It is pure and cost-effective comparing with others. That’s the reason I repeat order for 3 times in a month.
NMN PRO 500 is a marvel. I’m sharing my testimonial: after just a few days of taking the capsules, I have incredible energy—truly incredible—and my skin is more hydrated, with an extraordinary glow.
It improved energy
Good
Truly fee the difference!
NMN Pro 1000™ - Uthever® NMN, 1000 mg per serving, 60 capsules - 3 Pack
I bought this for my father and hope it works for him.
NMN Pro 300™ - Uthever® NMN - 300 mg, 30 capsules
Habe been taking it for a year, feel very good and with energy
I have been taking for 30 days and results are subtle. Looking forward to continue taking NMN for my overall health.
Not bad not good, really no results at all. Starting my second month so I’m just getting started. I was really hoping I’d start seeing some improvement in energy levels but I’m still exhausted and napping by 2. For reference I’m 66 yo and not very active. But I was hoping this would help me feel like moving more. Granted my lvls were probably severely depleted so going to take some time. I started on 500mg I think I’ll up it to the 1000 mg after this month.