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Cardiac manifestations of Lyme disease: a review.

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To describe the clinical features of cardiac manifestations of
Lyme disease, the most common vector-borne illness in North America, which occasionally results in cardiac involvement.


A review of the English-language clinical literature pertaining to
Lyme disease and
Lyme carditis indexed in MEDLINE from 1975 to 1995.


Studies describing diagnosis, clinical features, treatment or outcome were reviewed.


Cardiac complications of
Lyme disease may occur in up to 8% of patients. Cardiac manifestations occur in the early phase of the illness, at a median of 21 days from the onset of erythema migrans. Manifestations of
Lyme carditis include atrioventricular block, myopericarditis, intraventricular conduction disturbances, bundle branch block and congestive heart failure. Temporary cardiac pacing may be required in up to a third of cases and complete recovery occurs in most (greater than 90%) patients. The overall prognosis of
Lyme carditis is very good, although recovery may be delayed and late complications such as dilated cardiomyopathy may occur.


Lyme disease is a tick-borne spirochetal infection caused by Borrelia burgdorferi. Cardiac complications of
Lyme disease generally occur in the early phase and include conduction system disturbances, myopericarditis and congestive heart failure.

Can J Cardiol. 1996 May;12(5):503-6. Review

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