Have you heard about LDN (Low Dose Naltrexone) for chronic Lyme disease? I am excited to say that I have been taking it successfully for chronic pain although it took awhile to kick in. There appear to be many amazing health benefits for taking LDN, including the inhibition of cancerous cell growth!
The major mechanism of action of LDN involves blocking the body’s opioid/narcotic receptors for just a very few hours (rather than the all-day blockade caused by the 50mg dosage). Those are the same receptors used by the body’s endorphins. The body responds to this by greatly increasing its endorphin production, and those higher levels last all day — far after the blockade by LDN has ended. Endorphins turn out to be the major normalizer/upregulator of one’s immune system.
It is best to start low at between .5 and 1.5 mg and work up to as much as 4.5 mg (vs 50 – 300 mg for drug addicts or alcoholics). My doctor prescribed 2 weeks at 1.5 mg, 2 weeks at 3 mg and three weeks ago I moved up to my full dose of 4.5 mg. I didn’t notice any improvement during the first month (although I know a few people who felt benefits at 2 mg), but about two weeks into the full dose I started to notice a marked improvement in pain relief and general well-being.
I have read that some people who had NOT been diagnosed with Lyme and were treated with LDN for fibromyalgia had a worsening of symptoms due to an apparent immune response. This patient writes from LDN Yahoo group:
“LDN can and usually does backfire with untreated Lyme disease. That is how I discovered that I have Lyme, because I tried LDN and everything got much worse, and prompted me to get testing done that revealed Lyme. Since then I have heard the same story repeated again and again from many people with Lyme. In my opinion, the ability to tolerate LDN is a good test of the relative severity of infection when you do have Lyme. LDN seems to “turn the lights on” for your immune system and reveal everything that was previously invisible. If there’s nothing there, you’re fine. If your body is riddled with spirochetes, you’re in for a BUMPY ride as all-out warfare commences. Lyme sufferers that have been on antibiotics for extended lengths of time or have less severe cases seem to do alright with LDN.”
Some people experience a relief in symptoms much faster than I did, but like most treatments it takes consistency for lasting relief.
Some of the other things LDN has found to be helpful in treating:
ALS (Lou Gehrig’s disease)
Autism (see Jacob’s amazing piano-playing story in the MOVIE)
Chronic fatigue syndrome
Inflammatory bowel disease (IBS)
Multiple sclerosis (MS)
Myasthenia Gravis (MG)
Primary lateral sclerosis (PLS)
Primary Biliary Cirrhosis
Progressive Supranuclear Palsy
Stiff Person Syndrome (SPS)
Systemic Lupus (SLE)
Additionally, LDN has been found helpful in combating the following cancers:
Brain tumors (both astrocytoma and glioblastoma)
Colon & Rectal Cancer
Head and neck squamous cell carcinoma
Lung Cancer (both small cell and non-mmall cell)
Lymphocytic Leukemia (chronic)
Lymphoma (Hodgkin’s and Non-Hodgkin’s)
Prostate Cancer (untreated)
Renal Cell Carcinoma
Where do you get it?
Like all prescription medications LDN must be prescribed by a MD, and it is usually mixed by an independent lab and sent directly to you rather than through a pharmacy. No, it is not covered by insurance but thankfully it is relatively inexpensive – between $30 and $40 per month.
For more information:
LDN – The Movie
The LDN Book by Linda Elsegood
the mechanics of LDN
LymeDiseaseResource.com is written by Jenna Seaver, a writer who is a victim of Lyme disease herself. Formerly a successful entrepreneur, competitive equestrian, wife, mother to six and grandmother to seven, Jenna is now single having lost most of family, friends and unfortunately all her horses, dogs and cats as a result of this disease. Finally recovering (however slowly) after dozens of failed protocols Jenna now focuses on writing, Lyme activism and internet marketing.