NMN Pro 250™ Sustained Release 6 pack Product Image
NMN Pro 250™ Sustained Release Supplement Facts and Label Information
NMN Pro 250™ Sustained Release Certificate of Analysis

The #1 longevity formula trusted by 200,000+ customers 

NMN Pro 250™ Sustained Release - Uthever® NMN- Living Machine™

60 Tablets • 250mg • 6 Pack • SKU: PH598F

Title

Power Through Your Day with Sustained NAD+ Support

Time- Released NMN for Steady Energy, Resilience & Longevity

•  Increases NAD+ levels by 38%*17 
•  Optimizes mitochondrial performance*3-5,7,8   
•  Enhances cellular energy*2,4-8  

•  Supports DNA repair & stability*1,2,4,5,7-9   

•  Helps combat the effects of aging*1-6,8,9 

Title

1 Pack

3 Pack
$292.95
$418.50

Triple Lab Tested

Doctor Formulated 

Manufactured in the USA

Advancing Health & Longevity since 1988

For over 36 years, ProHealth has been committed to building the world’s highest-quality supplements—driven by innovation, integrity, and a passion for advancing healthy aging. That same commitment led our team of doctors to develop a breakthrough, patent-pending formula designed to boost NAD⁺ through three distinct biological pathways—delivering one of the most advanced, full-spectrum approaches to cellular health and longevity available today.*

Pioneering Longevity 

Since 1988 

For over 36 years, ProHealth has been dedicated to crafting the world’s highest-quality supplements—rooted in innovation, integrity, and a passion for healthy aging. With a long-standing A+ rating from the Better Business Bureau, our reputation for purity and potency has made us one of the most trusted names in the industry. 

 

Our commitment to scientific rigor, premium sourcing, and results you can feel continues to drive everything we do.  

The Gold Standard for Cellular Energy

Reclaim youthful energy, strengthen physical performance, and elevate your quality of life by restoring your body’s NAD+ levels daily.


 NMN Powder fuels energy production, fights fatigue, and targets all 12 hallmarks of aging—supporting lasting vitality from now through your golden years.*

The Gold Standard for Cellular Energy

Title

Reclaim youthful energy, strengthen physical performance, and elevate your quality of life by restoring your body’s NAD+ levels daily.
 

NMN Pro Sustained Release fuels energy production, fights fatigue, and targets all 12 hallmarks of aging—supporting lasting vitality from now through your golden years.*

Cellular Energy 
Starts Here.

NAD⁺ (nicotinamide adenine dinucleotide) is a vital coenzyme found in every cell of your body, essential for converting nutrients into energy, activating DNA-repair enzymes (PARPs), and regulating sirtuins—proteins that influence gene expression and longevity. As a cornerstone of cellular metabolism, NAD⁺ supports energy production, DNA integrity, and healthy aging.*12-16  

   

By middle age, NAD⁺ levels in some tissues can drop by up to 50%, slowing down cellular repair and metabolic efficiency. One of the most effective ways to maintain NAD⁺ is with Nicotinamide Mononucleotide (NMN)—a clinically studied form of vitamin B3 that supports the body’s natural NAD⁺ production pathways, helping you feel energized, resilient, and more youthful as you age.*1,3,10-16  

The Advantage of Sustained Release

What Makes Ours Better?

NAD+ Support That Goes the Distance

NMN Pro 250™ Sustained Release is formulated as a smart-release tablet that protects NMN through digestion and delivers it gradually in the intestines 

— ensuring steady NAD⁺ support  for ongoing cellular health*18 

Fewer Doses, Better Results

Sustained release provides consistent benefits — without the need for frequent dosing. 

Steady, Lasting Energy Production

Maintain consistent cellular energy levels throughout the day—without the peaks and crashes. 

Smart Release for Better Bioavailability 

Our controlled-release tablet technology ensures maximum absorption, so your cells get more from every milligram.  

Featuring Clinically Studied Niagen® NR 

We use Niagen®, the gold standard in NAD+ research. Backed by over 400 studies and multiple human trials, it’s proven to significantly raise NAD+ levels and support mitochondrial function—essential for energy and cellular health.* 

The Technology Behind Steady 

NAD+ Support

Unlike standard NMN capsules that release all at once, NMN Pro 250™ uses a pH-sensitive gel-barrier matrix to slow and protect NMN release.  

 

This delivery system activates in the stomach’s acidic environment, forming a gel that shields NMN from degradation. As the tablet moves into the intestines, NMN is gradually released— helping maintain consistent NAD⁺ levels and cellular energy production*18 

Why Ours Is So Effective.

The Gold Standard

Uthever® NMN (Nicotinamide Mononucleotide) is the ultimate NAD+ precursor, serving as an essential building block in the NAD+ synthesis pathway*1-7,9 

Scientifically Supported

Uthever® NMN is the world’s first clinically studied NMN brand, demonstrating both efficacy and a strong safety profile in human trials*10 

37 Trillion Benefits

NMN helps fuel energy production and optimize cellular function across trillions of cells—and vital organs—throughout your body*2,4-8

Rapid Results

NMN starts boosting NAD+ levels within 24 hours, with substantial increases observed over days to weeks in a dose-dependent manner*1,2,4-7,9 

Triple Lab Tested

Every product is tested three times by independent 3rd-party labs to ensure we meet the highest standards.

View Certificate of Analysis

Power Through Your Day 
with 38% Higher NAD+

Delivers NMN gradually for longer-lasting, elevated NAD+ levels.*18 

Our clinically tested NMN shows a 38% increase in NAD⁺ levels.*17 

Confidence In Every Bottle

100-Day Risk-Free Guarantee

We stand behind our products. If you're not satisfied please reach out to our Santa Barbara, CA office for a full refund within 100 days – no hassle, no questions.

Complete Transparency

In a market crowded with questionable supplements, we set ourselves apart by publishing third-party lab test results. We're commited to full transparency—so you know exactly what's in every bottle.

Free Shipping

Whether you're a first-time or returning customer, we offer free U.S. shipping on orders over $30—making your shopping experience even easier and more convenient.

Revitalize Your
Aging Cells*

Power Up Your Cells With NMN*

Nicotinamide Mononucleotide (NMN) is one of the most promising breakthroughs in longevity science. As a powerful vitamin B3 derivative and direct NAD+ precursor, it helps fuel the cellular energy, repair, and resilience needed to promote healthy, vibrant aging.*

Rebuild Your Body’s NAD+ Supply—Daily*

To maintain peak performance, your body requires a steady supply of NAD+. With NMN, you can effortlessly and continuously support your NAD+ levels. Research demonstrates that supplementing with NMN can elevate NAD+ levels in a dose-dependent manner, meaning higher doses yield greater increases in NAD+ concentrations.*1,2,4-7,9 

Fuel Cellular Energy Production*

NAD+ plays a vital role in converting food into usable energy at the cellular level. With NMN, you can optimize ATP production, leading to enhanced energy availability throughout the body. This boost in cellular energy not only supports physical performance but also contributes to enhanced quality of life.*2,4-8 

Target All 12 Hallmarks of Aging*

As we age, NAD+ levels naturally decline, making replenishment essential to support core longevity processes. NAD+ targets the root causes of aging, fueling essential enzymes like PARPs, which repair DNA and maintain cellular integrity, and activating Sirtuins, which regulate gene expression, inflammation, and stress response—key contributors to healthy aging.*1-6,8,9 

What Our Customers Are Saying

Formulas You Can Feel

ProHealth offers the world’s most comprehensive collection of NAD⁺-boosting supplements. From foundational ingredients like NR and NMN to next-generation compounds such as NMNH and Apigenin, our lineup spans every major pathway involved in NAD⁺ production and preservation. With multiple delivery forms, clinically studied ingredients, and advanced formulations designed to target energy, metabolism, brain health, and longevity, ProHealth is the global leader in NAD⁺ support—trusted by health seekers, researchers, and practitioners alike.

Frequently Asked Questions

Frequently Asked Questions

Frequently Asked Questions

What can I expect to feel when taking NMN?

NMN performs most of its functions on a cellular level and results are not always outwardly apparent. However, many individuals taking NMN report feeling increased energy levels, improved cognitive health, and enhanced exercise performance.

How quickly can I expect results from taking NMN?

While results may vary based on a variety of factors, NMN has been shown to significantly increase NAD+ levels in humans in as little as 30 days.

What dose of NMN do leading longevity researchers take?

Most experts in the longevity field take 1000mg of NMN daily.

Will NMN help me live longer?

Some research shows that NMN may extend lifespan due to its ability to increase NAD+ levels in the body. Research shows that increasing NAD+ levels in aged animals extends their lifespan.

Are there any side effects from NMN?

Clinical research conducted on humans taking NMN shows no clinically relevant adverse effects.

*These statements have not been evaluated by the Food and Drug Administration.This product is not intended to diagnose, treat, cure or prevent any disease.

Customer Reviews

Based on 79 reviews
92%
(73)
6%
(5)
1%
(1)
0%
(0)
0%
(0)
W
William V.D.J.
Real results

I’ve been using this product for a little over a month. I’ve experienced improved energy and focus.

D
Dana R.
NMN sustained

Good for night time usage

F
FRED F.

Makes me feel more energized.

R
Robert S.
NMN Pro is fantastic

I've been using this now for probably around 6 months, and my general well being seems to be above normal and my moods while never usually bad, are constantly great.

L
Lucila C.

NMN Pro 250™ Sustained Release - Uthever® NMN, 250 mg, 60 tabs - Living Machine™

J
J.T.
Excellent.

Great quality and effective. I’ve been taking this for 4 years with trans-resveratrol.

B
Brian K.
New customer

I recently started taking NMN Pro 250 once a day. The most noticeable change I noticed is my skin on my face. Skin seems smoother and pores are smaller. I'm a 66 year old male and definitely don't look it.

D
David J.
Research suggests it works

2 each day

S
Steven G.
Felt better

Hi, after taking this product for a month I have definitely felt better and will continue to use this product. Thanks for quality ingredients.

l
lashanda r.

so far i haven't really noticed a difference

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References

References

1Yi L et al. GeroScience. 2023;45(1):29-43.  

2Yamane T et al. Clin Nutr ESPEN. 2023;56:83-86.   

3Igarashi M et al. Npj Aging. 2022;8(1):5.   

4Okabe K et al. Front Nutr. 2022;9:868640.   

5Kim M et al. Nutrients. 2022;14(4):755.  

6Irie J et al. Endocr J. 2020;67(2):153-160.   

7Liao B et al. J Int Soc Sports Nutr. 2021;18(1):54.   

8Janssens GE et al. Nat Aging. 2022;2(3):254-263.  

9Katayoshi T et al. Sci Rep. 2023;13(1):2786.  

10Huang H. Front Aging. 2022;3:851698.  

11Yamaguchi S et al. Endocr J. 2024;71(2):153-169.   

12Orr ME et al. GeroScience. 2024;46(1):665-682.  

13Nascimento EBM et al. J Clin Endocrinol Metab. 2021;106(5):1437-1447.  

14Vreones M et al. Aging Cell. 2023;22(1):e13754.  

15Elhassan YS et al. Cell Rep. 2019;28(7):1717-1728.e6.  

16Martens CR et al. Nat Commun. 2018;9(1):1286.  

17Huang H. Front Aging. 2022;3:851698 

18Lallemand. GUARD Technology – Commercial Presentation. 2024.