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BPC-157 Ultra Probiotic - 60 capsules

SKU: PH725

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Beyond Probiotics: Total Digestive Wellness*

  • Promotes a balanced, thriving microbiome*1-3
  • Fortifies the gut lining and barrier integrity*2,4
  • Delivers butyrate and boosts natural production*2,3
  • Encourages a healthy inflammatory response in the GI tract*1,5,6
  • Supports gut-brain signaling for mood and cognition*1,4,7

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Next-Level Synbiotic Support

Introducing BPC-157 Ultra Probiotic — a groundbreaking formula that goes far beyond traditional probiotics. Instead of simply adding bacteria, this holistic blend takes a systems-level approach to digestive health. By reinforcing multiple layers of the gut ecosystem, it helps power whole-body vitality from the inside out. Because true wellness begins in the gut.*1-3,6-9

How It Works

It starts with BPC-157, a peptide naturally present in gastric juices. Pre-clinical research suggests BPC-157 may be supportive of mucosal repair, gut barrier integrity, and supporting healthy inflammatory responses within the GI tract. In short, it’s thought to play a role in the repair processes that keep your digestive system functioning smoothly.*4-6,10

Building on this foundation, we’ve added a strategic blend of prebiotics, probiotics, and postbiotics designed to amplify butyrate — the short-chain fatty acid that fuels and protects the colon. In the end, butyrate is the key metabolite that unifies and drives the benefits of this synbiotic system.*1-3

Why Butyrate Matters

Butyrate is the preferred fuel for colon cells — the cells that line and protect your gut. It helps keep the intestinal barrier strong, supports a balanced microbiome, and promotes healthy digestive function.1-3

The challenge? Many people don’t produce enough. Butyrate is generated by specific gut bacteria, yet modern diets are often low in the fibers and polyphenols those microbes need. When butyrate is lacking, colon cells turn to less efficient fuels like glucose. This shift can raise colonic pH, weaken barrier integrity, heighten inflammatory activity, and even affect gut–brain communication linked to mood and cognition.1-3

That’s why BPC-157 Ultra Probiotic goes beyond standard probiotics. Rather than just adding bacteria and hoping they take hold, it works at the root: delivering butyrate directly while enhancing your body’s natural production. More butyrate means stronger gut function... and whole-body wellness that radiates from the inside out.*1-3,6-9

What Makes Ours Better?

  • (Peptide) BPC-157: Formulated with Body Protection Compound-157, a peptide that works with your body to activate natural repair and renewal processes.*11
  • (Prebiotic) MicrobiomeX®: Citrus polyphenols clinically shown to shift your microbiome toward butyrate-producing bacteria.*1
  • (Probiotic) Clostridium butyricum: A spore-forming strain that survives stomach acid, activates in the intestines, and produces butyrate right where it’s needed most.*3
  • (Postbiotic) ButyraGen®: A targeted tributyrin that delivers butyrate directly to the colon. Clinical studies show a 26.4% improvement in digestive comfort.*2
  • A Holistic Strategy: By targeting structure, microbes, and metabolites, this formula supports multiple layers of the gut ecosystem for lasting digestive wellness.*1-3,6-9

The ProHealth Difference

  • Doctor-Formulated: Developed by our in-house science team in collaboration with leading wellness experts to address the root causes of aging.*
  • Triple Lab Tested: Rigorously tested three times by independent third-party labs to guarantee unmatched potency and purity.
  • Full Transparency: In an industry full of misleading claims, we publish our third-party lab results—so you always know exactly what’s in every bottle. 
  • Manufactured in the USA: Since 1988, we’ve proudly produced our supplements in FDA-regulated, GMP-certified facilities, ensuring the highest quality and safety standards.
  • 100-Day Risk-Free Guarantee: We stand behind our products. If you’re not completely satisfied, contact our Santa Barbara, CA office for a full refund—no hassle, no questions asked.

A Word from our Chief Science Officer

“With BPC-157 Ultra Probiotic, our goal was to create a formula that doesn’t just seed the gut, but actively reconditions it. We brought together a peptide to fortify the gut lining, clinically studied pre- and probiotics to nourish the microbiome, and targeted tributyrin to deliver butyrate where it’s needed most. The result is a true systems-level approach to digestive health, with butyrate at the center as the master metabolite.”

Pioneering Health and Wellness Products Since 1988

For over 36 years, ProHealth has been dedicated to crafting the world’s highest-quality supplements—rooted in innovation, integrity, and a passion for healthy aging. With a long-standing A+ rating from the Better Business Bureau, our reputation for purity and potency has made us one of the most trusted names in the industry. Our commitment to scientific rigor, premium sourcing, and results you can feel continues to drive everything we do.

Ingredient Information

BPC-157: A 15-amino acid peptide that supports cellular repair and tissue regeneration across the body — especially in the gut, joints, and soft tissues.*

References:

    1. Sost MM et al. Nutrients. 2021;13(11):3915.
    2. Dosz E et al. Nutraceuticals. 2025;5(2):14.
    3. Stoeva MK et al. Gut Microbes. 2021;13(1):1907272.
    4. Vukojevic J et a. Neural Regen Res. 2022;17(3):482-487.
    5. Cushman CJ et al. Yale J Biol Med. 2024;97(3):399-413.
    6. Klicek R et al. J Physiol Pharmacol Off J Pol Physiol Soc. 2013;64(5):597-612.
    7. Sikiric P et al. Pharm Basel Switz. 2023;16(5):676.
    8. Vukusic D et al. J Physiol Pharmacol Off J Pol Physiol Soc. 2024;75(1).
    9. Veljaca M et al. J Pharmacol Exp Ther. 1995;272(1):417-422.
    10. Gwyer D et a. Cell Tissue Res. 2019;377(2):153-159.
    11. Sikiric P et al. J Physiol Paris. 2001;95(1-6):283-288.
Supplement Facts
Serving Size: 2 Capsules
Servings Per Container: 30
Amount Per Serving %DV
MicrobiomeX® Prebiotic (from Orange and Grapefruit Fruit Extracts) 500 mg
ButyraGen® Tributyrin Complex 200 mg
Clostridium butyricum (1 Billion CFU) 100 mg
Body Protection Compound-157 (as BPC-157 Arginine Salt) 500 mcg
† Daily Value (DV) not established.

The MicrobiomeX® trademark and logo are property of BioActor B.V. ButyraGen® is a registered trademark of NutriScience Innovations, LLC.

REV.04.25

  • OTHER INGREDIENTS: Vegetable cellulose (capsule), acacia fiber, guar fiber, rosemary extract, microcrystalline cellulose, silica.
  • SUGGESTED DAILY USE: Take two (2) capsules daily, with or without food, or as directed by your healthcare professional.
  • CAUTION: For use by healthy adults only. Please consult your physician before use if you are pregnant or nursing, under the age of 18, or are undergoing treatment for a medical condition. Do not exceed the suggested use. KEEP OUT OF REACH OF CHILDREN. Store in a cool and dry place after opening.

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Frequently asked questions

BPC-157 Ultra Probiotic is designed for adults seeking advanced support for digestive health. It’s especially suited for those who haven’t experienced results with traditional probiotics. As with any supplement, individuals who are pregnant, nursing, taking medications, or managing a medical condition should consult a healthcare professional before use.*
No. Our probiotic strains are shelf-stable, so you can store the capsules at room temperature.
Yes, BPC-157 is considered safe when used as directed. It has been extensively studied in preclinical trials and has shown no significant side effects when taken at recommended dosages.
Yes. Every batch of our BPC-157 is independently tested to confirm it is free from LPS contamination.
Yes. BPC-157 is a protective peptide that naturally occurs in gastric juices, so the body is already familiar with it. Unlike many peptides that require injection, BPC-157 can be absorbed through the digestive tract. ProHealth’s formula uses a specialized Arginine Salt form to help maximize oral bioavailability, ensuring both stability and effectiveness.*