Calcium AKG Longevity - 60 Capsules by ProHealth Longevity

Support Energy Production, Bone Strength, and Metabolic Function With Age

  • Supports healthy aging processes
  • Supports heart, bone, and metabolic health
  • Supports cognitive vitality
  • Helps to boost antioxidant levels inside cells


View Certificate of Analysis »

Alpha-ketoglutarate (AKG) is a compound that is created naturally in the body but tends to diminish with age. In supplement form, AKG can be attached to a calcium salt (Ca-AKG), which has been studied for its role in supporting metabolic function and longevity (1).

Ca-AKG is involved in stimulating protein synthesis and energy production in the body, as it is a vital component of the Kreb’s cycle - the process that creates ATP (energy) from food. Ca-AKG is also a source of the essential amino acids needed to make collagen, which is a protein that helps to support bone and muscle health.

Additionally, Ca-AKG facilitates our internal recycling process known as autophagy, which removes dysfunctional cells, cell parts, and proteins from the body. Autophagy tends to decrease with age, so Ca-AKG may be able to help support this process.

Research has found that AKG lengthened lifespan in roundworms by up to 50% and delayed signs of aging (2). This may be because Ca-AKG activates AMP-activated protein kinase (AMPK) - a pathway that senses and maintains cellular energy balance by supporting the function of our cells' main energy hubs (the mitochondria) and healthy blood sugar control (3).

Ca-AKG has also been shown to boost cellular antioxidant levels in aged mice, which helped support the mice’s blood vessel elasticity - a measure of good cardiovascular health (4).


  1. Asadi Shahmirzadi A, Edgar D, Liao CY, et al. Alpha-Ketoglutarate, an Endogenous Metabolite, Extends Lifespan and Compresses Morbidity in Aging Mice. Cell Metab. 2020;32(3):447-456.e6. doi:10.1016/j.cmet.2020.08.004

  2. Chin R, Fu X, Pai M., et al. The metabolite α-ketoglutarate extends lifespan by inhibiting ATP synthase and TOR. Nature. 2014;510:397–40.

  3. Wu N, Yang M, Gaur U, Xu H, Yao Y, Li D. Alpha-Ketoglutarate: Physiological Functions and Applications. Biomol Ther (Seoul). 2016;24(1):1-8. doi:10.4062/biomolther.2015.078

  4. Niemiec T, Sikorska J, Harrison A, et al. Alpha-ketoglutarate stabilizes redox homeostasis and improves arterial elasticity in aged mice. J Physiol Pharmacol. 2011;62(1):37-43.

Label Information

Supplement Facts
Serving Size: 2 Capsules
Servings Per Container: 30
Amount Per Serving %DV
Calcium Alpha Ketoglutarate 1,000mg
† Daily Value not established
  • Suggested Use: Take 2 capsules daily, in the morning, with or without food.
  • Storage: Store in a cool, dry place after opening. Keep out of reach of children.
  • Contraindications: If you are pregnant, nursing, have a medical condition or are taking prescription drugs, consult your health care professional before using this product.
  • Other Ingredients: Organic Rice Flour, Vegetarian Capsule (Cellulose and water)
  • Contains No: Artificial colors, flavors, preseivatives, dairy, eggs, fish, shellfish, tree nuts, peanuts, wheat, gluten, soybean, corn, or yeast.


Customer Reviews

Based on 28 reviews
love love love

pure product

Michael R.
Higher Energy

Since taking ProHeath Calcium AKA my energy has never been higher. Have been Noticed the effects after just 2 week.

Justin H.
Calcium AKG Longevity

Good product

David R.

Calcium AKG Longevity (1,000 mg per 2 capsule serving, 60 capsules) by ProHealth Longevity

Brad N.

no side effects

Sue M.
So far, I'm very pleased

Great product

Frank M.
Dont feel any difference

Dont feel any difference

Charles N.
Excellent product

Immediate performance results.

Michael M.


Aviv S.

Great product