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NMN Pro™ Powder - Uthever® NMN, 500 grams

SKU: PH544

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Regular price $716.00
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All sales of the 500 gram bag are final once the bag has been opened.  We will not accept returns of unopened bags after 30 days from the date of your order.

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Combat Aging, Support Heart Health and Promote Muscle Strength

  • Uthever® NMN is the purest, highest quality pharmaceutical grade NMN in the world. It is third-party tested in an independent U.S. lab to verify its authenticity and purity.
  • NMN Pro Powder allows NMN to be absorbed directly into the blood vessels in the mouth and under the tongue, which increases the product's bioavailability. In this way, NMN avoids digestion in the gastrointestinal tract and can be more rapidly delivered into the bloodstream.
  • NMN supplementation has been found to support various parameters of health, including physical endurance and muscle strength, neurological function, heart health, body weight, and gene expression.
  • Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that is known to promote health and longevity by serving as a precursor to NAD+.

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Research-Supported Benefits:

Supports Longevity. Studies have shown that boosting NAD+ synthesis in the body extends the lifespan of yeast, worms and flies. (1)

Blood Sugar Regulation. As we age, we have more trouble processing glucose, leading to higher blood sugar. Supplemental NMN is shown to improve several markers of skeletal muscle glucose metabolism that are commonly dysregulated in people with metabolic disorders. (2)

Supports Metabolism and Healthy Weight. Although excessive body weight can develop at any age, adults over age 40 are particularly susceptible to age-related weight gain as metabolism slows down and body composition is altered to favor fat over lean muscle. As obese individuals have reductions in both NAD+ levels and ATP (energy) production, replenishing NAD+ through NMN can help to reverse this while improving metabolic pathways to maintain a healthy weight. (3,4,5)

Supports Healthy Cognition: Declining cognitive function with age is related to a reduced NAD+ levels that impair mitochondrial function. Replenishing NAD+ stores through NMN may be able to prevent this dysfunction. (6,7)

Supports Healthy Skin: In our 30s and 40s, the appearance of our skin can start to show signs of age. Several studies have examined how boosting NAD+ levels in the skin prevents premature skin aging or supports a healthier external appearance. (8,9)

References:

1. Fang EF, Kassahun H, Croteau DL, et al. NAD+ Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair. Cell Metab. 2016;24(4):566-581. doi:10.1016/j.cmet.2016.09.004

2. Feng Z, Qin Y, Huo F, et al. NMN recruits GSH to enhance GPX4-mediated ferroptosis defense in UV irradiation induced skin injury. Biochim Biophys Acta Mol Basis Dis. 2022;1868(1):166287. doi:10.1016/j.bbadis.2021.166287

3. Gopi S, Balakrishnan P. Evaluation and clinical comparison studies on liposomal and non-liposomal ascorbic acid (vitamin C) and their enhanced bioavailability. J Liposome Res. 2021;31(4):356-364. doi:10.1080/08982104.2020.1820521

4. Katayoshi T, Nakajo T, Tsuji-Naito K. Restoring NAD+ by NAMPT is essential for the SIRT1/p53-mediated survival of UVA- and UVB-irradiated epidermal keratinocytes. J Photochem Photobiol B. 2021;221:112238. doi:10.1016/j.jphotobiol.2021.112238

5. Kim M, Seol J, Sato T, Fukamizu Y, Sakurai T, Okura T. Effect of 12-Week Intake of Nicotinamide Mononucleotide on Sleep Quality, Fatigue, and Physical Performance in Older Japanese Adults: A Randomized, Double-Blind Placebo-Controlled Study. Nutrients. 2022;14(4):755. Published 2022 Feb 11. doi:10.3390/nu14040755

6. Kiss T, Nyúl-Tóth Á, Balasubramanian P, et al. Nicotinamide mononucleotide (NMN) supplementation promotes neurovascular rejuvenation in aged mice: transcriptional footprint of SIRT1 activation, mitochondrial protection, anti-inflammatory, and anti-apoptotic effects. Geroscience. 2020;42(2):527-546. doi:10.1007/s11357-020-00165-5

7. Liao B, Zhao Y, Wang D, Zhang X, Hao X, Hu M. Nicotinamide mononucleotide supplementation enhances aerobic capacity in amateur runners: a randomized, double-blind study. J Int Soc Sports Nutr. 2021;18(1):54. Published 2021 Jul 8. doi:10.1186/s12970-021-00442-

8. Mills KF, Yoshida S, Stein LR, et al. Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice. Cell Metab. 2016;24(6):795-806. doi:10.1016/j.cmet.2016.09.013

9. Tarantini S, Valcarcel-Ares MN, Toth P, et al. Nicotinamide mononucleotide (NMN) supplementation rescues cerebromicrovascular endothelial function and neurovascular coupling responses and improves cognitive function in aged mice. Redox Biol. 2019;24:101192. doi:10.1016/j.redox.2019.101192

10. Wang X, Hu X, Yang Y, Takata T, Sakurai T. Nicotinamide mononucleotide protects against β-amyloid oligomer-induced cognitive impairment and neuronal death. Brain Res. 2016;1643:1-9. doi:10.1016/j.brainres.2016.04.060

11. Yoshino J, Mills KF, Yoon MJ, Imai S. Nicotinamide mononucleotide, a key NAD(+) intermediate, treats the pathophysiology of diet- and age-induced diabetes in mice. Cell Metab. 2011;14(4):528-536. doi:10.1016/j.cmet.2011.08.014

12. Yoshino M, Yoshino J, Kayser BD, et al. Nicotinamide mononucleotide increases muscle insulin sensitivity in prediabetic women. Science. 2021;372(6547):1224-1229. doi:10.1126/science.abe9985

Supplement Facts

Serving Size: 1 Level Scoop

Servings Per Container: 500
Amount Per Serving %DV
Uthever® β-Nicotinamide Mononucleotide 1 Gram
† Daily Value not established.
REV.06.21
  • Suggested Use: Place 1 level scoop under the tongue or mix in water, first thing in the morning, preferably on an empty stomach.
  • Storage: Stable at room temperature for up to two years.
  • Contraindications: If you are pregnant and/or nursing, consult your doctor before use.
  • Contains No: GMOs, dairy, egg, soy, gluten, wheat, fillers, solvents, chemicals or artificial colors or flavors.
  • Nicotinamide mononucleotide (NMN) is a derivative of the B-vitamin niacin that dramatically improves health and longevity by serving as a precursor to NAD+, a compound that plays a crucial role in energy production, metabolism and gene expression in the body. When we boost NMN levels in the body, we can enhance the biosynthesis of NAD+ and alleviate symptoms associated with depletion of this crucial nutrient. NMN supplementation has been found to improve various parameters of health, including physical endurance and muscle strength, brain health, heart health, body weight and gene expression.
  • NMN Pro Powder allows NMN to be absorbed directly into the blood vessels in the mouth and under the tongue, which increases the product's bioavailability. In this way, NMN avoids digestion in the gastrointestinal tract and can be more rapidly delivered into the bloodstream.
  • Only Clincially-Proven NMN. ProHealth’s NMN is the only clinically-proven NMN to boost NAD+ levels in a peer-reviewed, double-blind, placebo-controlled, published, clinical study. Results of the study indicated a 38% increase in NAD+ levels and 12-year reversal in biological age.
  • Unique Delivery Method. NMN Pro Powder allows NMN to be absorbed directly into the blood vessels in the mouth and under the tongue, which increases the product's bioavailability.
  • Solvent-Free. Compared to other NMN products, ours is made without any chemical solvents.
  • Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.
  • Third-Party Tested in the USA. Every batch is third-party tested in US laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.
Be Aware of Fake NMN: Fraudulent companies are always attempting to out-price competitors by using NMN fake ingredients to gain market share, which is not fair to you, the consumer, or the reputable companies, like ProHealth that spends time and resources to ensure a safe and pure NMN product.
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"I've tried product from other company, it doesn't feel as good as from ProHealth!"

- Napas L., Verified ProHealth Customer

Customer Reviews

Based on 876 reviews
91%
(800)
5%
(41)
2%
(17)
0%
(4)
2%
(14)
K
Kimberly D.
Healthier nails as well as thicker eyelashes—- wasn’t expecting that.

I recommend. It is a little pricey.

D
Donald W.
Better health

I've been taking 1 gram a day with a small amount of water first thing in the morning for over a year now and feel great. I enjoy excellent health and high energy levels. I plan to continue using NMN and buying from ProHealth Longevity because of the quality, service and price offered by the company.

A
Alicia P.
Good results so far

I've been using NMN Pro™ Powder - Uthever® NMN for over a month or so. The product seems pure and I've gotten positive results in my brain function, energy, and appetite.

D
Daniel R.
Very good

Very good

T
TKirkland
Better energy

After a week, saw better energy levels.

A
Austin
Good product

Always reliable, will continue to use

J
Jim S.

NMN Pro™ Powder - Uthever® NMN, 30 grams

C
CindyB

Great product! Have been using it for over a year.

J
Judith A.B.
NMN is Good Stuff

Our Zumba Teacher (who is 20 years younger than us) told us about NMN and we have been using 1 bag (100 Grams) for 3 months. We find that in the morning, being in Our mid 70’s we had a lot of aches and pains. My husband and I each take 1/2 scoop under our tongue, first thing in the morning and find that our aches and pains seem to leave and we seem to have more energy, We go to SNAP GYM and do 2 Zumba Classes and a Stretch class in between, three times a week, as well as an hour Spin class and a Spin 50/50 Class . Really helps us with our energy level. Very satisfied with NMN. Highly recommend!

D
Donald B.

NMN Pro™ Powder - Uthever® NMN, 100 grams

Frequently asked questions

NMN performs most of its functions on a cellular level and results are not always outwardly apparent. However, many individuals taking NMN report feeling increased energy levels, improved cognitive health, and enhanced exercise performance.
While results may vary based on a variety of factors, NMN has been shown to significantly increase NAD+ levels in humans in as little as 30 days.
Most experts in the longevity field take 1000mg of NMN daily.
Some research shows that NMN may extend lifespan due to its ability to increase NAD+ levels in the body. Research shows that increasing NAD+ levels in aged animals extends their lifespan.
Clinical research conducted on humans taking NMN shows no clinically relevant adverse effects.