Repetitive negative thought patterns are linked to an increased risk of Alzheimer's disease, dementia, and pre-dementia signs including a build-up of amyloid and tau proteins in the brain.

Sleep deprivation increased death in fruit flies and caused an accumulation of reactive oxygen species (ROS). When ROS were neutralized in the gut, severely sleep-deprived fruit flies had normal lifespans.

The gene C19ORF57 plays a role in male fertility, which could improve reproductive medicine practices. This gene plays a crucial role in repairing DNA damage during meiosis in male gonads.

Neurofilament light chains (NfL) are a biomarker of neurodegeneration, which can detect Alzheimer's disease (AD) sooner. NfL levels increase with age and in people with increased genetic risk of AD.