Longevity Articles

Differences in an astronaut’s bone response and recovery to microgravity are primarily explained by mission duration, and there may be therapeutic potential of NMN for bone regeneration in astronauts. Read more

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A summary of clinical studies from 2021 and 2022 show that NMN treatment impacts exercise capacity, sleep, and fatigue, and provide insight into safety and dosing strategies. Read more

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NMN supplementation boosts the NAD+ pool in the intestine and activates the signaling pathways related to antioxidant, anti-inflammatory, and barrier functions that support healthy intestinal aging. Read more

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The compound crocin—found in saffron—benefits learning, memory, and social interaction in stressed mice by regulating an enzyme that produces NMN, a precursor to the vital molecule NAD+. Read more

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NAD+ levels can be maintained or elevated by supplementing with a precursor to NAD+, like NMN. But which form of NMN is best — liposomal, powder, sublingual, or capsules? Read more

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ProHealth Longevity reviews the categories of natural products with properties that slow aging and promote healthy lifespan extension, and the mechanisms of targets for anti-aging evaluation. Read more

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The correction of NAD+ depletion in mouse nerve cells supports axonal health — the projections of neurons — in the face of blood sugar dysregulation or other stressors. Read more

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Supplementing with 300 mg of NMN per day for 60 days increases blood serum NAD+ levels, improves quality of life and physical endurance, and reduces insulin resistance. Read more

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NAD+ biosynthesis is vital for regulating production of the intestinal hormone GLP-1 and maintaining healthy blood sugar and metabolism, which can be achieved with supplemental NMN.  Read more

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Nicotinamide mononucleotide (NMN) and lycopene, an antioxidant found in tomatoes, support cognitive function and decrease oxidative stress in aging rats  and fight senescence in rat brain cells. Read more

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NMN was safe and well-tolerated at 250 mg per day for 12 weeks, supporting mobility, lower limb physical performance, and daytime energy levels — especially when taken in the evening. Read more

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Anti-aging researcher Dr. David Sinclair conducts cutting-edge research on longevity-supporting compounds like NMN, NR, and resveratrol.  Read more

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