Dr. Lapp on XMRV & Ampligen – Information that may “change the field of medicine forever”

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In his March 2011 ME-News newsletter, Dr. Charles Lapp, MD, director of the Hunter-Hopkins Center in Charlotte, NC, reports on findings presented by researchers at the March 3-6 Hemispherx Biopharma Investigators Meeting.

In this newsletter (at www.drlapp.net/meLetterMar2011.htm) Dr. Lapp clearly lays out the new science on gene sequencing in CFS patients, and analysis of XMRV subsets in Ampligen treatment studies – and explains what Ampligen is.

Key Points We Noted in Dr. Lapp’s Summary Are That:

• Hemispherx developed the experimental antiviral drug Ampligen – currently the only proposed treatment for CFS  – and has supported CFS research for more than 22 years. The FDA has indicated Ampligen may be “approvable” as a therapy for CFS subject to treatment of larger numbers of patients “to assure safety and efficicacy.”

• When XMRV incorporates itself into a host’s own genomic DNA, the result is a combination DNA called a “chimera.”

• When cell death (apoptosis) occurs, these “chimeras are spilled into the bloodstream.”

• A company called Chronix Biomedical, which has developed a very fast way to map genomes, has found chimeras with XMRV genes in the genomes of CFS patients.

• As Dr. Lapp states, “The Chronix technology is wonderful news for PWCs (people with CFS), because if XMRV or MLV can be clearly shown to cause CFS, then we will have an inexpensive and unique marker for the disorder.”

• Not available commercially yet, the test will be used in future Hemispherx CFS studies.

• When Hemispherx studied 208 CFS patients whose exercise tolerance improved on Ampligen in trials – based on whether they were XMRV positive or negative – the analysis suggested that the one-third who tested XMRV positive “have an edge in responding to Ampligen.”

• About one-third of Dr. Lapp’s patients in the ongoing Ampligen ‘cost recovery’ treatment study have “achieved very significant global improvement.”

• Hemispherx plans to monitor the XMRV factor in the ongoing Ampligen treatment study at Hunter Hopkins (still inviting applicants) and Dr. Daniel Peterson’s Lake Tahoe clinic.

• Dr. Lucinda Bateman’s clinic in Salt Lake City will soon resume treatments, and Hemispherx plans to add several more US study sites – “in addition to sites in Mexico and Argentina.”

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3 thoughts on “Dr. Lapp on XMRV & Ampligen – Information that may “change the field of medicine forever””

  1. Ly45nn says:

    I was wondering if there are proposed studies of XMRV AND Ampligen in Canada. Let me know. Great article, thanks.

  2. sagallagherwarden says:

    Dear Drs.

    Do you have any plans on being in cities near or around Youngstown, Ohio–like Pittsburgh, Pa. Akron, Ohio, or Canton, Ohio, etc.?

    Is there any way I can be part of the study and/or treatment? I am diagnosed with CFS and have had it for 17 lousy years!!! I am grateful for any help you could give me. Thank you.

    Warm Regards,
    Sherry Gallagher Warden
    330-788-5868

  3. earthdog2000 says:

    I am So excited to know that I may be able to try this new medication someday soon! Any info on when this will be available to the public? Any trials being done in Reno, Nevada?
    I appreciate this article so much!
    Julie in Reno, Nevada

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